#!/usr/bin/env python
# -*- coding: utf-8 -*-
"""
It generates the list of allowed candidate fusion genes. This list is hard coded
inhere and it is manually curated from publications.



Author: Daniel Nicorici, Daniel.Nicorici@gmail.com

Copyright (c) 2009-2014 Daniel Nicorici

This file is part of FusionCatcher.

FusionCatcher is free software: you can redistribute it and/or modify
it under the terms of the GNU General Public License as published by
the Free Software Foundation, either version 3 of the License, or
(at your option) any later version.

FusionCatcher is distributed in the hope that it will be useful,
but WITHOUT ANY WARRANTY; without even the implied warranty of
MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
GNU General Public License for more details.

You should have received a copy of the GNU General Public License
along with FusionCatcher (see file 'COPYING.txt').  If not, see
<http://www.gnu.org/licenses/>.

By default, FusionCatcher is running BLAT aligner
<http://users.soe.ucsc.edu/~kent/src/> but it offers also the option to disable
all its scripts which make use of BLAT aligner if you choose explicitly to do so.
BLAT's license does not allow to be used for commercial activities. If BLAT
license does not allow to be used in your case then you may still use
FusionCatcher by forcing not use the BLAT aligner by specifying the option
'--skip-blat'. Fore more information regarding BLAT please see its license.

Please, note that FusionCatcher does not require BLAT in order to find
candidate fusion genes!

This file is not running/executing/using BLAT.

"""
import sys
import os
import optparse
import symbols

if __name__ == '__main__':

    #command line parsing

    usage = "%prog [options]"
    description = """It generates the list of allowed candidate fusion genes (which are manually curated from scientific articles)."""
    version = "%prog 0.12 beta"

    parser = optparse.OptionParser(usage=usage,description=description,version=version)

    parser.add_option("--organism",
                      action = "store",
                      type = "string",
                      dest = "organism",
                      default = "homo_sapiens",
                      help="""The name of the organism for which the list of allowed candidate fusion genes is generated, e.g. homo_sapiens, mus_musculus, etc. Default is '%default'.""")

    parser.add_option("--output",
                      action="store",
                      type="string",
                      dest="output_directory",
                      default = '.',
                      help="""The output directory where the list of allowed candidate fusion genes is generated. Default is '%default'.""")

    parser.add_option("--skip-filter-overlap",
                      action="store_true",
                      dest="skip_filter_overlap",
                      default = False,
                      help="""If set then it filters out the known fusion genes where the (i) genes are fully overlapping, or (ii) the genes are partially overlapping and are on the same strand. Default is '%default'.""")

    (options,args) = parser.parse_args()

    # validate options
    if not (options.output_directory
            ):
        parser.print_help()
        sys.exit(1)


    #
    #
    #

    print "Generating the list of allowed/known fusion genes..."
    fusions = dict()

    # manual curation from papers

    fusions['rattus_norvegicus'] = []

    fusions['mus_musculus'] = []

    fusions['canis_familiaris'] = []

    fusions['homo_sapiens'] = [
        ['AADACL2','ENSA'],
        ['AAMDC','SLC12A7'],
        ['AASDH','LRRC66'],
        ['AASDH','PPAT'],
        ['ABCA2','FYTTD1'],
        ['ABCA4','BCAR3'],
        ['ABCA5','PPP4R1L'],
        ['ABCB9','ZDHHC7'],
        ['ABCC8','VCL'],
        ['ABCG1','SLC37A1'],
        ['ABHD12','ZNF337'],
        ['ABHD3','ESCO1'],
        ['ABI1','MLL'],
        ['ABI1','PDSS1'],
        ['ABI2','MLL'],
        ['ABL1','BCR'],
        ['ABL1','CBFB'],
        ['ABL1','EML1'],
        ['ABL1','ETV6'],
        ['ABL1','EXOSC2'],
        ['ABL1','NUP214'],
        ['ABL1','RCSD1'],
        ['ABL1','SFPQ'],
        ['ABL1','ZMIZ1'],
        ['ABL2','ETV6'],
        ['ABL','BCR'],
        ['ABLIM2','DIP2C'],
        ['AC090627.1','THRA'],
        ['AC099850.1','TMEM49'],
        ['AC099850.1','VMP1'],
        ['ACACA','DDX52'],
        ['ACACA','MLL'],
        ['ACACA','MSI2'],
        ['ACACA','STAC2'],
        ['ACACA','UTP18'],
        ['ACAD10','MAPKAPK5'],
        ['ACAD9','C3ORF46'],
        ['ACBD6','RRP15'],
        ['ACE','KPNB1'],
        ['ACER1','MLL'],
        ['ACPL2','RASA2'],
        ['ACPP','SKIL'],
        ['ACRBP','ENO2'],
        ['ACS2','ETV6'],
        ['ACSF2','MED1'],
        ['ACSL3','ETV1'],
        ['ACSL6','ETV6'],
        ['ACTB','GLI1'],
        ['ACTB','MAP7D1'],
        ['ACTN2','TBCE'],
        ['ACTN4','EIF3K'],
        ['ACTN4','MLL'],
        ['ACTR3B','MLL3'],
        ['ACTR8','IL17RB'],
        ['ADAM17','SLC23A3'],
        ['ADAM17','YWHAQ'],
        ['ADAM9','PLEKHA2'],
        ['ADAMTS12','PXDNL'],
        ['ADAMTS17','ADAMTSL3'],
        ['ADAMTS19','RUNX1'],
        ['ADAMTS19','SLC27A6'],
        ['ADCY3','SOS1'],
        ['ADCY4','RABGGTA'],
        ['ADD1','HTT'],
        ['ADD1','POMC'],
        ['ADD3','NUP98'],
        ['ADK','C10ORF11'],
        ['ADK','DLG5'],
        ['ADNP','C20ORF132'],
        ['ADRBK1','IGHMBP2'],
        ['ADRBK2','SGSM3'],
        ['ADRBK2','WWC1'],
        ['AF10','HEAB'],
        ['AF10','MLL'],
        ['AF10','PICALM'],
        ['AF6','MLL'],
        ['AF9','MLL'],
        ['AFF1','DSCAML1'],
        ['AFF1','MLL'],
        ['AFF3','BCL2'],
        ['AFF3','FGFR2'],
        ['AFF3','MLL'],
        ['AFF3','RUNX1'],
        ['AFF4','MLL'],
        ['AFX','PAX3'],
        ['AGAP1','IGFBP2'],
        ['AGAP2','CYP27B1'],
        ['AGAP2','MARS'],
        ['AGAP2','TMEM67'],
        ['AGAP3','JAZF1'],
        ['AGAP5','BMS1P4'],
        ['AGK','BRAF'],
        ['AGK','WDR60'],
        ['AGL','C9ORF25'],
        ['AGPAT5','MCPH1'],
        ['AGPAT5','MSRA'],
        ['AGXT2L2','CYB5R1'],
        ['AHCTF1','NAAA'],
        ['AHCYL1','FGFR2'],
        ['AHCYL1','RAD51C'],
        ['AHCYL2','MKLN1'],
        ['AHCYL2','TMEM178B'],
        ['AHCY','TAX1BP1'],
        ['AHNAK','HNRNPUL2'],
        ['AHNAK','KAT5'],
        ['AIDA','KCNH1'],
        ['AIFM1','FGF13'],
        ['AIM1','SOBP'],
        ['AK126539','TXNDC11'],
        ['AK7','PAPOLA'],
        ['AKAP11','MRPS31'],
        ['AKAP12','ESR1'],
        ['AKAP1','RNF43'],
        ['AKAP6','EGLN3'],
        ['AKAP6','NPAS3'],
        ['AKAP9','ANKIB1'],
        ['AKAP9','BRAF'],
        ['AKAP9','PON2'],
        ['AKT3','C1ORF150'],
        ['AKT3','MAGI3'],
        ['AL035685.1','CSE1L'],
        ['AL121578.2','SYTL5'],
        ['ALDH7A1','SLC9A7'],
        ['ALG14','CNN3'],
        ['ALG5','PIGU'],
        ['ALK','ATIC'],
        ['ALK','C2ORF44'],
        ['ALK','CARS'],
        ['ALK','CLTC'],
        ['ALK','CLTCL1'],
        ['ALK','CTLC'],
        ['ALK','DCTN1'],
        ['ALK','EML4'],
        ['ALK','FN1'],
        ['ALK','HIP1'],
        ['ALK','KIF5B'],
        ['ALK','KLC1'],
        ['ALK','MSN'],
        ['ALK','MYH9'],
        ['ALK','NPM'],
        ['ALK','NPM1'],
#        ['ALK','NTRK1'],
        ['ALK','PPFIBP1'],
        ['ALK','PTPN3'],
        ['ALK','RANBP2'],
        ['ALK','RNF213'],
        ['ALK','SEC31A'],
        ['ALK','SEC31L1'],
        ['ALK','SQSTM1'],
        ['ALK','STRN'],
        ['ALK','TFG'],
        ['ALK','TMP3'],
        ['ALK','TMP4'],
        ['ALK','TPM3'],
        ['ALK','TPM4'],
        ['ALK','VCL'],
        ['ALS2CR16','ALS2CR8'],
        ['ALX3','RECK'],
        ['AMACR','SDK1'],
        ['AML1','FOG2'],
        ['AML1','JAK2'],
        ['AML1','MDS1'],
        ['AML1','TEL'],
        ['AMPH','FDFT1'],
        ['ANAPC1','RGPD3'],
        ['ANAPC7','SLC2A13'],
        ['ANK1','RTN3'],
        ['ANK1','ZMAT4'],
        ['ANK2','ARHGAP10'],
        ['ANK3','CCDC6'],
        ['ANKHD1','C5ORF32'],
        ['ANKHD1','CYSTM1'],
        ['ANKHD1','PCDH1'],
        ['ANKRD13A','FLJ40142'],
        ['ANKRD23','ANKRD39'],
        ['ANKRD28','FNDC3B'],
        ['ANKRD28','NSD1'],
        ['ANKRD28','NUP98'],
        ['ANKS1B','CCDC53'],
        ['ANO1','ZNF331'],
        ['ANO4','KIF21A'],
        ['ANO4','TMTC3'],
        ['ANP32B','GABBR2'],
        ['ANTXRL','RGS10'],
        ['AOF2','C1ORF201'],
        ['AP002806.1','KIRREL3'],
        ['AP002856.4','KIRREL3'],
        ['AP1GBP1','TOB1'],
        ['AP1M2','SRP68'],
        ['AP2A1','ZNF544'],
        ['AP2A2','SBF2'],
        ['AP2A2','SFMBT1'],
        ['AP3S1','LMAN2'],
        ['APBA1','DEGS1'],
        ['APBB3','SRA1'],
        ['APC2','C19ORF25'],
        ['APEH','SHISA5'],
        ['APH1B','USP3'],
        ['API2','MALT1'],
        ['APIP','PVT1'],
        ['APIP','SLC1A2'],
        ['APOA1','APOC3'],
        ['APOC2','APOC4'],
        ['APPBP2','PHF20L1'],
        ['ARFGEF2','FAM65C'],
        ['ARFGEF2','ITCH'],
        ['ARFGEF2','SULF2'],
        ['ARHGAP19','DRG1'],
        ['ARHGAP20','BRWD3'],
        ['ARHGAP21','ENKUR'],
        ['ARHGAP26','MLL'],
        ['ARHGAP27','SH3D20'],
        ['ARHGAP32','TIMM23'],
        ['ARHGAP9','GLI1'],
        ['ARHGAP9','RUNX2'],
        ['ARHGDIG','ASTN2'],
        ['ARHGEF12','KCTD2'],
        ['ARHGEF12','MLL'],
        ['ARHGEF17','MLL'],
        ['ARHGEF17','SHANK2'],
        ['ARHGEF25','B4GALNT1'],
        ['ARHGEF3','C8ORF38'],
        ['ARHGEF4','PLEKHB2'],
        ['ARID1A','BEND5'],
        ['ARID1A','HOIP'],
        ['ARID1A','MAST2'],
        ['ARID1A','PRKD1'],
        ['ARID1A','RNF31'],
        ['ARID1A','UBR4'],
        ['ARID1B','TIAM2'],
        ['ARIH2','CAMP'],
        ['ARL17A','KANSL1'],
        ['ARL17B','KIAA1267'],
        ['ARL6IP1','RPS15A'],
        ['ARNT2','MESDC2'],
        ['ARNT','ETV6'],
        ['ARNT','TEL'],
        ['ARPC2','TXNDC15'],
        ['ARPC4','TTLL3'],
        ['ART4','C12ORF69'],
        ['ASAP1','PVT1'],
        ['ASB9','WDR59'],
        ['ASCC1','CBARA1'],
        ['ASCC2','ZMAT5'],
        ['ASCC3','UBE2E1'],
        ['ASH1L','C1ORF61'],
        ['ASL','CRCP'],
        ['ASNA1','RFX1'],
        ['ASNA1','WDR20'],
        ['ASPL','TFE3'],
        ['ASPSCR1','TFE3'],
        ['ASTN2','PAPPA'],
        ['ASTN2','PDIA2'],
        ['ASXL1','BPIL3'],
        ['ASXL1','PAX5'],
        ['ASXL2','MYST3'],
        ['ATAD1','PTEN'],
        ['ATAD1','STAMBPL1'],
        ['ATAD3B','NIPAL3'],
        ['ATE1','FGFR2'],
        ['ATE1','PVT1'],
        ['ATF1','EWS'],
        ['ATF1','EWSR1'],
        ['ATF1','FUS'],
        ['ATG14','FUT8'],
        ['ATG16L2','LRP5'],
        ['ATG4B','DTYMK'],
        ['ATG5','PDSS2'],
        ['ATG7','RAF1'],
        ['ATIC','ALK'],
        ['ATP10A','C12ORF49'],
        ['ATP10B','EBF1'],
        ['ATP1A1','NOTCH2'],
        ['ATP1A2','DCAF8'],
        ['ATP1B4','CHST11'],
        ['ATP5L','TEAD1'],
        ['ATP5O','TIAM1'],
        ['ATP6V0A1','MB'],
        ['ATP8A2','RUNX1'],
        ['ATR','EIF2AK1'],
        ['ATR','TOP3B'],
        ['ATRX','RPS6KA6'],
        ['ATXN2','RPL6'],
        ['AURKA','BCAS4'],
        ['AUTS2','BAZ1B'],
        ['AUTS2','PAX5'],
        ['AVIL','PPM1H'],
        ['AVIL','TMEM120B'],
        ['AVIL','TSFM'],
        ['AXIN1','LMF1'],
        ['AXL','MBIP'],
        ['B4GALNT1','FAM19A2'],
        ['B4GALNT1','SLC26A10'],
        ['B4GALNT1','TSFM'],
        ['B4GALT1','CSPP1'],
        ['BAG4','FGFR1'],
        ['BAG6','SLC44A4'],
        ['BAHD1','IVD'],
        ['BAI2','HS3ST4'],
        ['BAIAP2L1','FGFR3'],
        ['BAIAP2L2','SLC16A8'],
        ['BAIAP2','SLC38A10'],
        ['BANF1','EIF1AD'],
        ['BAT3','SLC44A4'],
        ['BATF2','FARS2'],
        ['BAZ1A','SNX6'],
        ['BAZ2A','ETV6'],
        ['BAZ2A','FSIP1'],
        ['BCAN','NTRK1'],
        ['BCAR4','CLEC16A'],
        ['BCAS1','ZBP1'],
        ['BCAS3','BCAS4'],
        ['BCAS3','ERBB2'],
        ['BCAS3','HOXB9'],
        ['BCAS3','MAP3K3'],
        ['BCAS3','MED13'],
        ['BCAS3','TG'],
        ['BCAS3','TRIM37'],
        ['BCAS4','ZMYND8'],
        ['BCL10','IGH@'],
        ['FGFR3','IGH@'],
        ['WHSC1','FGFR3'],
        ['BCL10','IGK@'],
        ['BCL11A','GRIP2'],
        ['BCL11A','IGH@'],
        ['BCL11B','IKZF2'],
        ['BCL11B','NKX2-5'],
        ['BCL11B','RNA28S5'],
        ['BCL11B','TLX3'],
        ['BCL11B','TRD@'],
        ['BCL1','IGH@'],
        ['BCL2','IGH@'],
        ['BCL2','IGHG1'],
        ['BCL2','IGK@'],
        ['BCL2','IGL@'],
#        ['BCL2L12','PRMT1'],
        ['BCL2L13','SLC39A9'],
        ['BCL2L14','ETV6'],
        ['BCL2L1','BMP8B'],
        ['BCL2L1','DEM1'],
        ['BCL2L1','HM13'],
        ['BCL2L1','PPT1'],
        ['BCL2L1','RIMS3'],
        ['BCL2L1','RLF'],
        ['BCL2L1','ZNF643'],
        ['BCL2L1','ZNF684'],
        ['BCL2','MYC'],
        ['BCL3','IGH@'],
        ['BCL3','IGK@'],
        ['BCL3','IGL@'],
        ['BCL3','MYC'],
        ['BCL6','CIITA'],
        ['BCL6','DMRT1'],
        ['BCL6','EIF4A2'],
        ['BCL6','FBXO18'],
        ['BCL6','GAPDH'],
        ['BCL6','GAS5'],
        ['BCL6','GRHPR'],
        ['BCL6','H4FM'],
        ['BCL6','HIST1H4I'],
        ['BCL6','HSP90AA1'],
        ['BCL6','HSP90AB1'],
        ['BCL6','IGH@'],
        ['BCL6','IGK@'],
        ['BCL6','IGL@'],
        ['BCL6','IKAROS'],
        ['BCL6','IKZF1'],
        ['BCL6','IL21R'],
        ['BCL6','LCP1'],
        ['BCL6','LPP'],
        ['BCL6','LRMP'],
        ['BCL6','MBNL1'],
        ['BCL6','MYC'],
        ['BCL6','NACA'],
        ['BCL6','NAPA'],
        ['BCL6','PIM1'],
        ['BCL6','POU2AF1'],
        ['BCL6','RAF1'],
        ['BCL6','RHOH'],
        ['BCL6','SFRS3'],
        ['BCL6','SNHG5'],
        ['BCL6','SRSF3'],
        ['BCL6','ST6GAL1'],
        ['BCL6','TFRC'],
        ['BCL7A','C12ORF42'],
        ['BCL8','IGH@'],
        ['BCL9','IGH@'],
        ['BCL9','IGL@'],
        ['BCL9L','MLL'],
        ['BCLAF1','GRM1'],
        ['BCOR','CCNB3'],
        ['BCOR','RARA'],
        ['BCOR','ZC3H7B'],
        ['BCR','FGFR1'],
        ['BCR','JAK2'],
        ['BCR','LZTR1'],
        ['BCR','PDGFRA'],
        ['BCR','RET'],
        ['BCS1L','MLL'],
        ['BEND5','NTRK2'],
        ['BEST3','NUP107'],
        ['BEST3','TMTC2'],
        ['BF104016','NSMCE2'],
        ['BGLAP','PMF1'],
        ['BICC1','FGFR2'],
        ['BICC1','LDB1'],
        ['BIRC3','MALT1'],
        ['BIRC6','LTBP1'],
        ['BMPER','ZNF416'],
        ['BMPR1A','LIPA'],
        ['BMPR1B','SMARCAD1'],
        ['BMPR2','FAM117B'],
        ['BRAF','CLCN6'],
        ['BRAF','FAM131B'],
        ['BRAF','FCHSD1'],
        ['BRAF','FXR1'],
        ['BRAF','GNAI1'],
        ['BRAF','KIAA1549'],
        ['BRAF','MACF1'],
        ['BRAF','MKRN1'],
        ['BRAF','NRF1'],
        ['BRAF','PAPSS1'],
        ['BRAF','QKI'],
        ['BRAF','RAF1'],
        ['BRAF','RNF130'],
        ['BRAF','SLC45A3'],
        ['BRAF','TRIM24'],
        ['BRCA2','TPP2'],
        ['BRD1','PAX5'],
        ['BRD3','C15ORF55'],
        ['BRD3','NUT'],
        ['BRD4','C15ORF55'],
        ['BRD4','NUT'],
        ['BRD4','RFX1'],
        ['BRE','FOSL2'],
        ['BRE','RBKS'],
        ['BRE','SEMA4C'],
        ['BRIP1','EGFR'],
        ['BRIP1','GPATCH8'],
        ['BRIP1','POLDIP2'],
        ['BRK1','VHL'],
        ['BRPF3','NUDT3'],
        ['BRPF3','STARD9'],
        ['BSG','NFIX'],
        ['BSG','RAB22A'],
        ['BSN','RBM6'],
#        ['BST1','CD38'],
        ['BTBD1','NTRK3'],
        ['BTBD7','SLC2A5'],
        ['BTG1','MYC'],
        ['BTL','ETV6'],
        ['BUB1B','SPRED1'],
        ['BX248273','CSPP1'],
        ['BX648577','CIITA'],
        ['C10ORF140','EIF4G3'],
        ['C10ORF18','NET1'],
        ['C10ORF26','SUFU'],
        ['C10ORF59','NFIA'],
        ['C11ORF1','KIAA0999'],
        ['C11ORF20','ESRRA'],
        ['C11ORF63','STARD10'],
        ['C11ORF67','SLC12A7'],
        ['C11ORF93','HYOU1'],
        ['C11ORF95','LTBP3'],
        ['C11ORF95','MAML2'],
        ['C11ORF95','MKL2'],
        ['C11ORF95','PRG2'],
        ['C11ORF95','RELA'],
        ['C11ORF95','YAP1'],
        ['C12ORF10','CTDSP2'],
        ['C12ORF11','RASSF8'],
        ['C12ORF42','TM7SF3'],
        ['C12ORF49','MDM2'],
        ['C12ORF4','EFCAB4B'],
        ['C12ORF56','LEMD3'],
        ['C12ORF59','XIAP'],
        ['C12ORF5','KIF21A'],
        ['C12ORF73','HSP90B1'],
        ['C14ORF166','KRAS'],
        ['C14ORF166','SLC25A1'],
        ['C15ORF21','ETV1'],
        ['C15ORF41','WWOX'],
        ['C16ORF11','RAB40C'],
        ['C16ORF14','RAB40C'],
        ['C16ORF70','ENKD1'],
        ['C16ORF75','CIITA'],
        ['C17ORF106','CDK3'],
        ['C17ORF57','NSF'],
        ['C17ORF75','NR1D1'],
        ['C17ORF80','GGNBP2'],
        ['C18ORF1','PARD6G'],
        ['C18ORF45','HM13'],
        ['C19MC','TTYH1'],
        ['C19ORF33','SPINT2'],
        ['C19ORF56','FBXL18'],
        ['C1ORF100','CEP170'],
        ['C1ORF151','RCC2'],
        ['C1ORF177','DHCR24'],
        ['C1ORF185','NRD1'],
        ['C1ORF226','NOS1AP'],
        ['C1ORF61','CCT3'],
        ['C1ORF61','RHBG'],
#        ['C1ORF74','IRF6'],
        ['C1ORF86','MUC1'],
        ['C1ORF95','TAF5L'],
        ['C1RL','LPCAT3'],
        ['C20ORF112','PAX5'],
        ['C20ORF151','DIDO1'],
        ['C21ORF91','ZNF638'],
        ['C22ORF25','RANBP1'],
        ['C2CD2L','ZNF585B'],
        ['C2CD3','MLL'],
        ['C2ORF43','PUM2'],
        ['C2ORF55','SERINC5'],
        ['C2ORF67','KIF1A'],
        ['C2ORF82','NBAS'],
        ['C3ORF27','EVI1'],
        ['C4ORF28','INPP4A'],
        ['C5ORF22','PDCD6'],
        ['C5ORF47','PDE4D'],
        ['C6ORF106','SPDEF'],
        ['C6ORF138','CAND1'],
        ['C6ORF138','HSP90AB1'],
        ['C6ORF204','SYTL3'],
        ['C6ORF211','ESR1'],
        ['C6ORF223','TMEM63B'],
        ['C6ORF225','TLK1'],
        ['C6ORF97','ESR1'],
        ['C6ORF97','PPP1R14C'],
        ['C7ORF10','HIBADH'],
        ['C7ORF16','SRRT'],
        ['C7ORF44','HECW1'],
        ['C7ORF49','WDR91'],
        ['C7ORF50','MACROD1'],
        ['C7ORF57','COBL'],
        ['C7ORF61','TSC22D4'],
        ['C8ORF37','CRTC1'],
        ['C8ORF38','PLEC1'],
        ['C8ORF47','PGCP'],
        ['C9ORF163','SEC16A'],
        ['C9ORF24','NFX1'],
        ['C9ORF25','POLN'],
        ['C9ORF25','ZCCHC7'],
        ['C9ORF93','FREM1'],
        ['CA7','USP22'],
        ['CABLES1','TM9SF4'],
        ['CABLES2','SNTA1'],
        ['CACNA2D3','CAPN11'],
        ['CACNA2D4','WDR43'],
        ['CACNB1','CCDC47'],
        ['CACNB1','PGAP3'],
        ['CADPS','SLC25A26'],
        ['CALB2','CYB5B'],
        ['CALCRL','MFSD6'],
        ['CALD1','GPATCH4'],
#        ['CALML4','CLN6'],
        ['CALU','CAP2'],
        ['CAMK4','SFXN1'],
        ['CAMSAP1','NOTCH1'],
        ['CAMTA1','FOXJ3'],
        ['CAMTA1','GPATCH3'],
        ['CAMTA1','MTOR'],
        ['CAMTA1','PGD'],
        ['CAMTA1','WWTR1'],
        ['CAND1','EGFR'],
        ['CAND1','PTCHD4'],
        ['CAN','DEK'],
        ['CANT1','ETV4'],
        ['CAP1','MACF1'],
        ['CAPN11','CPM'],
        ['CAPN11','PPM1H'],
        ['CAPN1','POLA2'],
        ['CAPRIN1','PDGFRB'],
        ['CAPS','JMJD2B'],
        ['CAPZA2','MET'],
        ['CAPZB','PAFAH2'],
        ['CAPZB','UBR4'],
        ['CARM1','SMARCA4'],
        ['CARM1','YIPF2'],
        ['CASC5','MLL'],
        ['CASD1','VWC2'],
        ['CASK','EML4'],
        ['CASP7','FGFR2'],
        ['CASP7','SRGAP1'],
        ['CATSPER2','PPIP5K1'],
        ['CAV1','ST7'],
        ['CAV3','SLC6A11'],
        ['CBFA2T3','GLIS2'],
        ['CBFA2T3','NFIA'],
        ['CBFA2T3','RUNX1'],
        ['CBFB','MYH11'],
        ['CBFB','RERG'],
        ['CBLC','RELB'],
        ['CBL','FBXO2'],
        ['CBL','MLL'],
        ['CBP','MOZ'],
        ['CBX5','DCD'],
        ['CBX7','ENTHD1'],
        ['CCBL1','GLE1'],
        ['CCDC101','NSMCE1'],
        ['CCDC102A','ZNF207'],
        ['CCDC117','HSCB'],
        ['CCDC127','TERT'],
        ['CCDC130','DOCK6'],
        ['CCDC142','MRPL53'],
        ['CCDC28A','NUP98'],
        ['CCDC43','YBX2'],
        ['CCDC46','SMURF2'],
        ['CCDC46','SUPT4H1'],
        ['CCDC46','TAOK1'],
        ['CCDC49','USP32'],
        ['CCDC57','NKD2'],
        ['CCDC67','VAV2'],
        ['CCDC6','FGFR2'],
        ['CCDC6','HPR'],
        ['CCDC6','PDGFRB'],
        ['CCDC6','RET'],
        ['CCDC6','ROS1'],
        ['CCDC81','PICALM'],
        ['CCDC82','FAM19A2'],
        ['CCDC85C','SETD3'],
        ['CCDC88C','PDGFRB'],
        ['CCDC88C','SMEK1'],
        ['CCDC9','KIAA0134'],
        ['CCKBR','NGLY1'],
        ['CCL2','MCP1'],
        ['CCM2','OGDH'],
        ['CCNB1IP1','HMGA2'],
        ['CCNB1IP1','PLEKHG1'],
        ['CCNB1IP1','PVT1'],
        ['CCND1','FSTL3'],
        ['CCND1','IGH@'],
        ['CCND1','IGHG1'],
        ['CCND1','IGK@'],
        ['CCND1','IGL@'],
        ['CCND1','TROP2'],
        ['CCND2','IGH@'],
        ['CCND2','IGK@'],
        ['CCND2','IGL@'],
        ['CCND2','TRA@'],
        ['CCND2','TRB@'],
        ['CCND3','IGH@'],
        ['CCND3','IGL@'],
        ['CCNE2','FAM82B'],
#        ['CCP110','TMC5'],
        ['CCT3','PPP2R2B'],
        ['CD151','TSPAN4'],
        ['CD274','CIITA'],
        ['CD2AP','MARCH9'],
        ['CD302','LY75'],
        ['CD37','MAP3K13'],
        ['CD3D','MLL'],
        ['CD44','FGFR2'],
        ['CD44','PDHX'],
        ['CD44','SLC1A2'],
        ['CD46','USH2A'],
        ['CD4','M6PR'],
        ['CD70','ETV6'],
        ['CD74','NRG1'],
        ['CD74','NTRK1'],
        ['CD74','ROS1'],
        ['CD81','SPAG6'],
        ['CD9','CDKN1A'],
        ['CDADC1','GORASP2'],
        ['CDC2L1','SLC35E2'],
        ['CDC42BPA','RASAL1'],
        ['CDC42BPB','PET112'],
        ['CDC42EP1','FGFR1'],
        ['CDC42EP2','NFAT5'],
        ['CDC42SE2','FAM114A2'],
        ['CDC42SE2','TRDMT1'],
        ['CDC6','IKZF3'],
        ['CDC73','FAM172A'],
        ['CDCA5','PHLDB1'],
        ['CDH11','UBFD1'],
        ['CDH11','USP6'],
        ['CDH1','CIRH1A'],
        ['CDH23','KLK5'],
        ['CDHR2','CLTB'],
        ['CDK12','LASP1'],
        ['CDK12','MED1'],
        ['CDK17','KCNC2'],
        ['CDK2','RAB5B'],
        ['CDK4','MDM2'],
        ['CDK4','TSFM'],
        ['CDK4','TSPAN31'],
        ['CDK5RAP2','MEGF9'],
        ['CDK5RAP2','PDGFRA'],
        ['CDK6','EVI1'],
        ['CDK6','FAM133B'],
        ['CDK6','IGH@'],
        ['CDK6','IGK@'],
        ['CDK6','IGL@'],
        ['CDK6','MLL'],
        ['CDK6','TLX3'],
        ['CDKAL1','E2F3'],
        ['CDKAL1','EGFR'],
        ['CDKAL1','RANBP9'],
        ['CDKN2A','FAM230A'],
        ['CDKN2A','TRA@'],
        ['CDKN2B','DGKD'],
        ['CDKN2D','WDFY2'],
        ['CDX1','IRF2BP2'],
        ['CDX2','ETV6'],
        ['CDYL','FARS2'],
        ['CDYL','RERE'],
        ['CEACAM8','RELB'],
        ['CEACAM8','SIRT2'],
        ['CEBPA','IGH@'],
        ['CEBPB','IGH@'],
        ['CEBPD','IGH@'],
        ['CEBPE','IGH@'],
        ['CEBPE','TRA@'],
        ['CEBPG','IGH@'],
        ['CELSR3','IP6K1'],
        ['CENPK','LGR5'],
        ['CENPK','MLL'],
        ['CEP110','FGFR1'],
        ['CEP128','NOTCH2'],
        ['CEP164','MLLT10'],
        ['CEP170','RAD51B'],
        ['CEP1','FGFR1'],
        ['CEP250','ZMYND8'],
        ['CEP55','RET'],
        ['CEP85L','PDGFRB'],
        ['CEP85L','ROS1'],
        ['CEP85','TMPRSS2'],
        ['CERS2','PIGC'],
        ['CEV14','PDGFRB'],
#        ['CFH','CFHR1'],
        ['CGA','ZFYVE9'],
        ['CGNL1','CYP19A1'],
        ['CHCHD10','VPREB3'],
        ['CHCHD7','PLAG1'],
        ['CHD1','FRAP1'],
        ['CHD1','MTOR'],
        ['CHD7','PVT1'],
        ['CHD7','TOX'],
        ['CHD9','CRLF3'],
        ['CHEK2','PPP2R2A'],
        ['CHEK2','THOC5'],
        ['CHGN','PSD3'],
        ['CHI3L1','GFAP'],
        ['CHIC1','MACROD1'],
        ['CHIC2','ETV6'],
        ['CHIC2','FIP1L1'],
        ['CHIC2','PDGFRA'],
        ['CHID1','CORO7'],
        ['CHID1','MAGMAS'],
        ['CHMP1A','ZC3H18'],
        ['CHMP3','PIGF'],
        ['CHN2','RALY'],
        ['CHN2','TSPAN33'],
        ['CHOP','EWS'],
        ['CHOP','FUS'],
        ['CHOP','TLS'],
        ['CHPT1','MED13L'],
        ['CHPT1','UTP20'],
        ['CHRM1','MRPS28'],
        ['CHST11','FAM70A'],
        ['CHST11','IGH@'],
        ['CIC','DUX4'],
        ['CIC','FOXO4'],
        ['CIDEB','NOP9'],
        ['CIITA','DEXI'],
        ['CIITA','FLJ27352'],
        ['CIITA','PDCD1LG2'],
        ['CIITA','RALGDS'],
        ['CIITA','RUNDC2A'],
        ['CIP29','MLL'],
        ['CIRH1A','TMCO7'],
        ['CITED1','HDAC8'],
        ['CIT','ETV6'],
        ['CIT','ETV7'],
        ['CIT','FGFR2'],
        ['CIT','RFC5'],
        ['CKLF','CMTM4'],
        ['CLCA2','RUNX1'],
        ['CLCN3','NEK1'],
        ['CLCN6','BRAF'],
        ['CLDN10','DNAJC3'],
        ['CLDN7','CUX1'],
        ['CLDN9','THOC6'],
        ['CLEC16A','TXNDC11'],
        ['CLIC4','PLOD1'],
        ['CLIC4','SRRM1'],
        ['CLIP2','GTF2I'],
        ['CLOCK','SCFD2'],
        ['CLOCK','TMEM165'],
        ['CLPTM1L','SERBP1'],
        ['CLPTM1L','GLIS3'],
        ['CLSTN1','STOX1'],
        ['CLTA','UBE2R2'],
        ['CLTC','TFE3'],
        ['CLTC','TMEM49'],
        ['CLTC','VMP1'],
        ['CLU','MYH14'],
        ['CLVS1','PVT1'],
        ['CMAHP','MLL'],
        ['CMAS','PIK3C2G'],
        ['CMTM7','GLB1'],
        ['CMYA5','MIIP'],
        ['CNBP','USP6'],
        ['CNTNAP2','GCFC2'],
        ['CNTNAP2','KIAA2013'],
        ['CNTRL','FGFR1'],
        ['COBL','ELMO1'],
        ['COBL','GLI3'],
        ['COBL','SEPT14'],
        ['COG1','RNA28S5'],
        ['COL12A1','COL4A5'],
        ['COL12A1','GRM1'],
        ['COL14A1','FAM84B'],
        ['COL14A1','SKAP1'],
        ['COL1A1','PDGFB'],
        ['COL1A1','USP6'],
        ['COL1A2','PLAG1'],
        ['COL6A3','CSF1'],
        ['COL9A2','RLF'],
        ['COL9A3','MAN2A2'],
        ['COMMD1','EHBP1'],
        ['COMT','GAPDH'],
        ['COMT','MED15'],
        ['COPG1','RASA2'],
        ['COQ10A','USP5'],
        ['CORO7','VPS13D'],
        ['COX6C','HMGA2'],
        ['COX6C','HMGIC'],
        ['COX6C','LAPTM4B'],
        ['CPLX2','UBXD8'],
        ['CPM','LEMD3'],
        ['CPM','LYZ'],
        ['CPM','MDM2'],
        ['CPM','PDZRN4'],
        ['CPM','RAP1B'],
        ['CPM','STAT6'],
        ['CPNE1','PI3'],
        ['CPNE1','PREX1'],
        ['CPNE8','RUNX1'],
        ['CPSF3L','EPHB2'],
        ['CPSF6','FGFR1'],
        ['CPSF6','KCNMB4'],
        ['CPT1A','HRASLS2'],
        ['CPT1C','JAZF1'],
        ['CREB1','EWS'],
        ['CREB1','EWSR1'],
        ['CREB1','PARD3B'],
        ['CREB1','TMEM131'],
        ['CREB3L1','EWSR1'],
        ['CREB3L1','FUS'],
        ['CREB3L2','EWSR1'],
        ['CREB3L2','FUS'],
        ['CREB3L2','PPARG'],
        ['CREB3L4','CRTC2'],
        ['CREB5','CWC27'],
        ['CREB5','KCNH2'],
        ['CREBBP','KAT6A'],
        ['CREBBP','MLL'],
        ['CREBBP','MYST3'],
        ['CREBBP','MYST4'],
        ['CREBBP','SLX4'],
        ['CREM','EWSR1'],
        ['CRKL','KLHL22'],
        ['CRKL','MAPK1'],
        ['CRKRS','FBXL20'],
        ['CRKRS','TMEM104'],
        ['CRLF2','IGH@'],
        ['CRLF2','P2RY8'],
        ['CRLS1','KCNK17'],
        ['CROCC','NBPF1'],
        ['CRTAC1','EXOSC1'],
        ['CRTC1','KLHL26'],
        ['CRTC1','MAML1'],
        ['CRTC1','MAML2'],
        ['CRTC3','MAML2'],
        ['CRYBB2','KIAA1671'],
        ['CRYL1','PSPC1'],
        ['CSF1R','MEF2D'],
        ['CSF1R','RBM6'],
        ['CSF1','S100A10'],
        ['CSGALNACT2','RET'],
        ['CSMD2','TMEM222'],
        ['CSMD3','MYC'],
        ['CSNK2A1','DDX39B'],
        ['CT45A2','MLL'],
        ['CTAGE5','KHDRBS3'],
#        ['CTAGE5','MIA2'],
        ['CTAGE5','PSMA3'],
        ['CTAGE5','SIP1'],
#        ['CTBS','GNG5'],
        ['CTDSP2','DCUN1D4'],
        ['CTDSP2','MARS'],
        ['CTDSP2','MON2'],
        ['CTDSP2','RAP1B'],
        ['CTL4','NEU1'],
        ['CTNNA1','JMJD1B'],
        ['CTNNB1','FGFR2'],
        ['CTNNB1','PLAG1'],
#        ['CTSC','RAB38'],
#        ['CTSD','IFITM10'],
        ['CUL1','DPP6'],
        ['CUX1','FGFR1'],
        ['CUX1','PRKRIP1'],
        ['CWC22','WNK1'],
        ['CWC25','USP32'],
        ['CXCL17','PSG3'],
        ['CXCR4','MAML2'],
        ['CXCR7','HMGA2'],
        ['CXORF15','SYAP1'],
        ['CXORF67','MBTD1'],
        ['CYP19A1','TMOD3'],
        ['CYP19A1','TRPM7'],
        ['CYP2C19','FAM190B'],
        ['CYP2C19','SNX9'],
        ['CYP2U1','PERLD1'],
        ['CYP39A1','EIF3K'],
        ['CYP51A1','GBAS'],
        ['CYTH1','EIF3H'],
        ['CYTH1','EXOC7'],
        ['CYTSB','PDGFRB'],
        ['DAB1','RYR3'],
        ['DAB2IP','MLL'],
        ['DACH1','PAX5'],
        ['DAPK3','FERMT1'],
        ['DAZAP1','DYM'],
        ['DAZAP1','MEF2D'],
        ['DBNDD1','NAT8L'],
        ['DCC','IGF1R'],
        ['DCP1A','MLL'],
        ['DCPS','MLL'],
        ['DCPS','ST3GAL4'],
        ['DCTD','ECE2'],
        ['DCUN1D4','RAB3IP'],
        ['DCUN1D4','SCN2A'],
        ['DDIT3','EWSR1'],
        ['DDIT3','FUS'],
        ['DDIT3','GLI1'],
        ['DDIT3','MARS'],
        ['DDX10','NUP98'],
        ['DDX19B','SF3B3'],
        ['DDX20','TBX15'],
        ['DDX3X','MLLT10'],
        ['DDX3X','PRKD1'],
        ['DDX42','MAP3K3'],
        ['DDX55','GTF2H3'],
        ['DDX5','DEPDC6'],
        ['DDX5','DEPTOR'],
        ['DDX5','ETV4'],
        ['DDX5','IQCG'],
        ['DDX6','IGH@'],
        ['DEK','NUP214'],
        ['DENND1C','SURF1'],
        ['DEPDC1B','ELOVL7'],
        ['DGKB','MIPOL1'],
        ['DGKD','SPP2'],
        ['DHX35','ITCH'],
        ['DHX37','NCOR2'],
        ['DHX57','MAP4K3'],
        ['DHX57','TMEM178'],
        ['DIDO1','TTI1'],
        ['DIP2B','TAF8'],
        ['DIP2B','TMBIM6'],
        ['DIP2C','LARGE'],
        ['DIP2C','PDGFRA'],
        ['DIRC2','TIA1'],
        ['DIRC3','HSPBAP1'],
        ['DISC1','DISC1FP1'],
        ['DKFZP586P0123','SHANK2'],
        ['DLEC1','ODZ4'],
        ['DLEU2','PSPC1'],
        ['DLG2','UNC45B'],
        ['DLGAP1','GRLF1'],
        ['DMD','IL1RAPL1'],
        ['DMD','SSR1'],
        ['DMGDH','JMY'],
        ['DMRT1','RFX3'],
        ['DNAH9','RABEP1'],
        ['DNAJA2','NETO2'],
        ['DNAJB1','PRKACA'],
        ['DND1','WDR55'],
        ['DNER','PSMD1'],
        ['DNM2','NMRK2'],
        ['DNMBP','TACC2'],
        ['DNMT1','KEAP1'],
        ['DNMT3B','MDM4'],
        ['DOCK1','DPCD'],
        ['DOCK5','STARD3'],
        ['DOCK6','RAVER1'],
        ['DOK5','STARD3'],
        ['DOT1L','HES6'],
        ['DPF2','METTL12'],
        ['DPF2','POLA2'],
        ['DPM1','GRID1'],
        ['DPM1','MTMR2'],
        ['DPY19L2','PPFIA2'],
        ['DPY19L2','PPM1H'],
        ['DPYS','RIMS2'],
        ['DSE','FHL5'],
        ['DSP','RREB1'],
        ['DSTYK','PIK3C2B'],
        ['DTD1','PDGFRB'],
        ['DUSP10','PRDM16'],
        ['DUSP22','IGHG1'],
        ['DUX4','EWSR1'],
        ['DYDC2','TSPAN14'],
        ['DYNC1I1','IMMP2L'],
        ['DYNC1LI1','GADL1'],
        ['DYNLL1','SMS'],
        ['E1AF','EWS'],
        ['E2A','HLF'],
        ['E2A','TFPT'],
        ['E2F1','TAT'],
        ['E2F3','ER'],
        ['E2F3','LINC00340'],
        ['E2F5','FER1L6'],
        ['E2F7','NAV3'],
        ['EBF1','FBXL17'],
        ['EBF1','FEM1C'],
        ['EBF1','HMGA2'],
        ['EBF1','KCNN2'],
        ['EBF1','PVT1'],
        ['EBF3','TSPAN15'],
        ['EDIL3','MKLN1'],
        ['EEF1A1','TG'],
        ['EEF1E1','RREB1'],
        ['EEFSEC','MLL'],
        ['EEN','MLL'],
        ['EFNA5','PCDHB7'],
        ['EGFL6','RAB9A'],
        ['EGFR','ERP44'],
        ['EGFR','FANCC'],
        ['EGFR','FKBP9L'],
        ['EGFR','GASP'],
        ['EGFR','GNS'],
        ['EGFR','KIAA0573'],
        ['EGFR','LANCL2'],
        ['EGFR','MDM2'],
        ['EGFR','PDE1C'],
        ['EGFR','PDGFC'],
        ['EGFR','POLD1'],
        ['EGFR','PPARGC1A'],
        ['EGFR','PSPH'],
        ['EGFR','SDK1'],
        ['EGFR','SEC61G'],
        ['EGFR','SEPT14'],
        ['EGFR','VOPP1'],
        ['EGFR','VSTM2A'],
        ['EHBP1','NRF1'],
        ['EHF','NFIA'],
        ['EHMT2','SLC44A4'],
        ['EIF2AK1','ATR'],
        ['EIF2AK3','PRKD3'],
        ['EIF2C3','THRAP3'],
        ['EIF2C3','ZP2'],
        ['EIF3A','SFXN4'],
        ['EIF3E','RSPO2'],
        ['EIF3H','FAM65C'],
        ['EIF3H','TRPS1'],
        ['EIF4A1','PHOSPHO1'],
        ['EIF4A3','TSPEAR'],
        ['EIF4E2','HJURP'],
        ['EIF4G3','MAN1C1'],
        ['EIF4G3','ZNF683'],
        ['EIF4H','GTF2I'],
        ['ELF3','RNPEP'],
        ['ELF4','ERG'],
        ['ELK4','SLC45A3'],
        ['ELKS','RET'],
        ['ELL','MLL'],
        ['ELMO2','RAE1'],
        ['ELMOD3','RSAD2'],
        ['ELN','PAX5'],
        ['EMID2','GGCT'],
        ['EML5','HMGA2'],
        ['ENL','MLL'],
        ['ENOSF1','YES1'],
        ['ENOX1','TYRO3'],
        ['ENPP2','PLEC'],
        ['ENPP2','PLEC1'],
        ['ENTPD1','PDLIM1'],
        ['ENTPD5','FAM161B'],
        ['ENTPD7','IDE'],
        ['EP300','MLL'],
        ['EP300','MYST3'],
        ['EP400','PHF1'],
        ['EP400','TRIT1'],
        ['EP400','YEATS4'],
        ['EPB41L5','ZDHHC5'],
        ['EPC1','PHF1'],
        ['EPHB2','NBPF3'],
        ['EPOR','IGH@'],
        ['EPS15','MLL'],
        ['EPYC','UHRF1BP1'],
        ['ERBB2','IKZF3'],
        ['ERBB4','EZR'],
        ['ERC1','PDGFRB'],
        ['ERC1','RET'],
        ['ERC1','WNK1'],
        ['ERCC2','KLC3'],
        ['ERCC2','MARK4'],
        ['ERCC2','POU6F2'],
        ['ERF','GSK3A'],
        ['ERG','EWS'],
        ['ERG','EWSR1'],
        ['ERG','FKBP5'],
        ['ERG','FUS'],
        ['ERG','HERPUD1'],
        ['ERG','NDRG1'],
        ['ERG','PTEN'],
        ['ERG','SLC45A3'],
        ['ERG','SPINK1'],
        ['ERG','TMPRSS2'],
        ['ERLIN2','FGFR1'],
        ['ERN1','ST14'],
        ['ERO1L','FERMT2'],
        ['ERP44','MRPL50'],
        ['ERRFI1','SSR2'],
        ['ERVK3-1','FGFR1'],
        ['ERVWE1','IGH@'],
        ['ESD','TDRD3'],
        ['ESPN','ZBTB48'],
        ['ESR1','CCDC170'],
        ['ESR1','LATS1'],
        ['ESR1','MYB'],
        ['ESRP1','RAF1'],
        ['ESRRG','SMYD3'],
        ['EST14','ETV1'],
        ['ETO','RUNX1'],
        ['ETV1','EWS'],
        ['ETV1','EWSR1'],
        ['ETV1','FOXP1'],
        ['ETV1','HERV-K'],
        ['ETV1','HERVK17'],
        ['ETV1','HMGN2P46'],
        ['ETV1','HNRNPA2B1'],
        ['ETV1','HNRPA2B1'],
        ['ETV1','KLK2'],
        ['ETV1','MIPOL1'],
        ['ETV1','OR51E2'],
        ['ETV1','RP11-599B13.3'],
        ['ETV1','SLC45A3'],
        ['ETV1','SNURF'],
        ['ETV1','TMPRSS2'],
        ['ETV4','EWS'],
        ['ETV4','EWSR1'],
        ['ETV4','HERVK17'],
        ['ETV4','KLK2'],
        ['ETV4','SLC45A3'],
        ['ETV4','TMPRSS2'],
        ['ETV4','UBTF'],
        ['ETV5','SCL45A3'],
        ['ETV5','SLC45A3'],
        ['ETV5','TMPRSS2'],
        ['ETV6','EVI1'],
        ['ETV6','FGFR3'],
        ['ETV6','FLT3'],
        ['ETV6','GOT1'],
        ['ETV6','IGH@'],
        ['ETV6','JAK2'],
        ['ETV6','MDS2'],
        ['ETV6','MN1'],
        ['ETV6','MNX1'],
        ['ETV6','NCOA2'],
        ['ETV6','NIPBL'],
        ['ETV6','NTRK3'],
        ['ETV6','PAX5'],
        ['ETV6','PDGFRA'],
        ['ETV6','PDGFRB'],
        ['ETV6','PER1'],
        ['ETV6','PEX5'],
        ['ETV6','PTPRR'],
        ['ETV6','RUNX1'],
        ['ETV6','STL'],
        ['ETV6','SYK'],
        ['ETV6','SYN1'],
        ['ETV6','TTL'],
        ['ETV6','YTHDF2'],
        ['ETV7','GTF2I'],
        ['EU154352','PLXNA2'],
        ['EVI1','NRIP1'],
        ['EVI1','RPN1'],
        ['EVI1','RUNX1'],
        ['EWS','FEV'],
        ['EWS','FIL1'],
        ['EWS','FLI1'],
        ['EWS','NR4A3'],
        ['EWS','POU5F1'],
        ['EWSR1','CREB3L1'],
        ['EWSR1','FEV'],
        ['EWSR1','FLI1'],
        ['EWSR1','NFATC1'],
        ['EWSR1','NFATC2'],
        ['EWSR1','NR4A3'],
        ['EWSR1','PATZ1'],
        ['EWSR1','PBX1'],
        ['EWSR1','POU5F1'],
        ['EWSR1','SMARCA5'],
        ['EWSR1','SP3'],
        ['EWSR1','WT1'],
        ['EWSR1','YY1'],
        ['EWSR1','ZNF278'],
        ['EWSR1','ZNF384'],
        ['EWSR1','ZNF444'],
        ['EWS','SP3'],
        ['EWS','TEC'],
        ['EWS','UQCRH'],
        ['EWS','WT1'],
        ['EWS','ZNF278'],
        ['EWS','ZSG'],
        ['EXOC3L2','LIPE'],
        ['EXOC3L2','PLAUR'],
        ['EXOD1','IQCK'],
        ['EYS','PHF3'],
        ['EZR','ROS1'],
        ['FABP3','ZCCHC17'],
        ['FAF1','OSBPL9'],
        ['FAF1','SLC2A1'],
        ['FAHD1','NUDT16L1'],
        ['FAM102A','PTGES2'],
        ['FAM107B','FRMD4A'],
        ['FAM109A','SSH1'],
        ['FAM119B','MAPK1'],
        ['FAM119B','METTL1'],
        ['FAM119B','SRGAP1'],
        ['FAM132A','RLF'],
        ['FAM135A','PKIB'],
        ['FAM13C','SUFU'],
        ['FAM168A','SLC43A1'],
        ['FAM172A','PDE4D'],
        ['FAM172A','PPP2R2B'],
        ['FAM179A','PSPC1'],
        ['FAM188B','STEAP4'],
        ['FAM188B','VWC2'],
        ['FAM193A','FITM2'],
        ['FAM198B','TMEM144'],
        ['FAM19A2','SRGAP1'],
        ['FAM19A2','STRBP'],
        ['FAM19A2','ZNF462'],
        ['FAM22A','YWHAE'],
        ['FAM22B','YWHAE'],
        ['FAM33A','MYO1D'],
        ['FAM5C','PLA2G4A'],
        ['FAM70B','GAS6'],
        ['FAM71D','MPP5'],
        ['FAM71F1','SEPT14'],
        ['FAM84B','PTK2'],
        ['FBN3','POLR2A'],
        ['FBP17','MLL'],
        ['FBRSL1','TMTC3'],
        ['FBRS','ZNF771'],
        ['FBXL17','PJA2'],
        ['FBXL20','NOTCH2'],
        ['FBXL20','NSF'],
        ['FBXL20','SNF8'],
        ['FBXL20','TLK2'],
        ['FBXO38','TRIM40'],
        ['FBXO3','RDH13'],
        ['FBXW7','MLL3'],
        ['FCGR2B','IGH@'],
        ['FCHO1','MYO9B'],
        ['FCN1','KIAA1217'],
#        ['FCN3','MAP3K6'],
        ['FCRL4','IGH@'],
        ['FER1L6','RAD21'],
        ['FEV','FUS'],
        ['FGD4','LRRK2'],
        ['FGF3','RBM14'],
        ['FGF3','RBM4'],
        ['FGF3','SHANK2'],
        ['FGFR1','FGFR1OP'],
        ['FGFR1','FGFR1OP1'],
        ['FGFR1','FGFR1OP2'],
        ['FGFR1','FOP'],
        ['FGFR1','FOXO1'],
        ['FGFR1','GPR124'],
        ['FGFR1','HERVK'],
        ['FGFR1','LRRFIP1'],
        ['FGFR1','MYO18A'],
        ['FGFR1','NTM'],
        ['FGFR1','NUP98'],
        ['FGFR1OP1','RET'],
        ['FGFR1','PLAG1'],
        ['FGFR1','RHOT1'],
        ['FGFR1','TACC1'],
        ['FGFR1','TPR'],
        ['FGFR1','TRIM24'],
        ['FGFR1','WHSC1L1'],
        ['FGFR1','ZMYM2'],
        ['FGFR1','ZNF198'],
        ['FGFR1','ZNF791'],
        ['FGFR2','CCDC6'],
        ['FGFR2','COL14A1'],
        ['FGFR2','KIAA1598'],
        ['FGFR2','KIAA1967'],
        ['FGFR2','NSMCE4A'],
        ['FGFR2','OFD1'],
        ['FGFR2','PPAPDC1A'],
        ['FGFR2','SLC45A3'],
        ['FGFR2','TACC2'],
        ['FGFR2','TACC3'],
        ['FGFR2','ULK4'],
        ['FGFR2','WDR11'],
        ['FGFR3','IGH@'],
        ['FGFR3','IGHG1'],
        ['FGFR3','JAKMIP1'],
        ['FGFR3','TACC3'],
        ['FGGY','TESK2'],
        ['FHIT','HMGA2'],
        ['FIG4','SEC63'],
        ['FIGNL1','VOPP1'],
        ['FIG','ROS1'],
        ['FIP1L1','PDGFRA'],
        ['FIP1L1','RARA'],
        ['FKBP5','TMPRSS2'],
        ['FKBP8','SLC1A6'],
        ['FKHR','PAX3'],
        ['FKHR','PAX7'],
        ['FLI1','SCL45A3'],
#        ['FLJ00268','MTG1'],
        ['FLNA','MLL'],
        ['FLNB','LGALS12'],
        ['FLT3LG','RPS11'],
        ['FLVCR1','LYST'],
        ['FMN2','NVL'],
        ['FNBP1','MLL'],
        ['FNDC3B','TNIK'],
        ['FOSB','SERPINE1'],
        ['FOXK2','HEXDC'],
        ['FOXM1','SLC2A14'],
        ['FOXO1A','PAX3'],
        ['FOXO1A','PAX7'],
        ['FOXO1','PAX3'],
        ['FOXO1','PAX7'],
        ['FOXO3','MLL'],
        ['FOXO4','MLL'],
        ['FOXO4','PAX3'],
        ['FOXP1','IGH@'],
        ['FOXP1','MIPEP'],
        ['FOXP1','PAX5'],
        ['FOXP1','PPP1R2'],
        ['FOXP1','RYBP'],
        ['FREM2','MTRF1'],
        ['FRMD4A','PFKP'],
        ['FRS2','KIF5A'],
        ['FRS2','LYZ'],
        ['FRYL','MLL'],
        ['FRYL','OCIAD2'],
        ['FTO','HERPUD1'],
        ['FUS','CREB3L1'],
        ['FUS','CREB3L2'],
        ['FUS','POU5F1'],
        ['G2E3','SPRED2'],
        ['GABBR2','NOTCH1'],
        ['GALNT7','ORC4L'],
        ['GAPVD1','ZNF483'],
        ['GART','IFNGR2'],
        ['GAS6','RASA3'],
        ['GAS7','MLL'],
        ['GAS7','RCVRN'],
        ['GATA1','MYB'],
        ['GATAD2A','NFIX'],
        ['GATAD2B','NUP210L'],
        ['GATAD2B','TNFSF18'],
        ['GATSL1','GTF2I'],
        ['GBAS','PCLO'],
        ['GBAS','UBXN2A'],
        ['GCGR','LRRC45'],
        ['GCN1L1','MSI1'],
        ['GCN1L1','PLA2G1B'],
        ['GDPD5','RELT'],
        ['GFAP','TPT1'],
        ['GGT1','IGSF3'],
        ['GGT5','USP18'],
        ['GIGYF2','NGEF'],
        ['GIGYF2','TRPM8'],
        ['GIT1','SHMT1'],
        ['GIT2','PDGFRB'],
        ['GK5','METTL15'],
        ['GLG1','GRM5'],
        ['GLI1','MARS'],
        ['GLIPR2','NUDT2'],
        ['GLYR1','SLC9A8'],
        ['GMDS','TMEM189'],
        ['GMPS','MLL'],
        ['GNA12','SHANK2'],
        ['GNAI1','BRAF'],
        ['GNAO1','TOX3'],
        ['GNB3','METAP2'],
        ['GNGT1','KRIT1'],
        ['GNL2','SF3A3'],
        ['GNS','PAWR'],
        ['GOLGA4','PDGFRB'],
        ['GOLGA5','RET'],
        ['GOLGB1','ILDR1'],
        ['GOLM1','MAK10'],
        ['GOLT1A','KISS1'],
        ['GOLT1A','PLEKHA6'],
        ['GOPC','ROS1'],
        ['GOSR1','NF1'],
        ['GOSR1','ZNF207'],
        ['GPATCH8','MPP2'],
        ['GPBP1L1','IPP'],
        ['GPBP1L1','MAST2'],
        ['GPBP1','YEATS2'],
        ['GPC2','MCM7'],
        ['GPHN','MLL'],
        ['GPIAP1','PDGFRB'],
        ['GPLD1','TDP2'],
        ['GPN1','SLC4A1AP'],
        ['GPNMB','SP4'],
        ['GPR128','TFG'],
        ['GPR133','TXNRD1'],
        ['GPR158','WAC'],
        ['GPR160','NCEH1'],
        ['GPR160','PRKCI'],
        ['GPR37L1','NAV1'],
#        ['GPR56','GPR97'],
        ['GPRC5C','RECQL5'],
        ['GPS2','MPP2'],
        ['GPS2','SENP3'],
        ['GPSN2','STRN4'],
        ['GPT','PPP1R16A'],
        ['GRAF','MLL'],
        ['GRB2','HHATL'],
        ['GRB7','PPP1R1B'],
        ['GREB1','MBOAT2'],
        ['GRIK4','GRM5'],
        ['GRIP1','PPM1H'],
        ['GRK1','TFDP1'],
        ['GRK5','STOX1'],
        ['GRM1','MEF2A'],
        ['GRM1','TBL1XR1'],
        ['GSDMA','THRA'],
        ['GSDMB','MED1'],
        ['GSDMB','ORMDL3'],
        ['GSDMB','TATDN1'],
        ['GSX2','SCFD2'],
        ['GTF2E2','GSR'],
        ['GTF2H3','SETD1B'],
        ['GTF2I','NCOA2'],
        ['GTPBP2','POLH'],
        ['GZMM','RERG'],
        ['H2AFX','WDR18'],
        ['HADHB','RBKS'],
        ['HARS2','ZMAT2'],
        ['HAS2','PLAG1'],
        ['HCFC1R1','THOC6'],
        ['HCMOGT1','PDGFRB'],
        ['HDAC1','SERINC2'],
        ['HDGF','S100A10'],
        ['HDHD1','MACROD1'],
        ['HDLBP','SCCPDH'],
        ['HEATR3','SMEK1'],
        ['HEI10','HMGIC'],
        ['HEPHL1','PANX1'],
        ['HER2','WIPF2'],
        ['HEY1','NCOA2'],
        ['HFM1','SLCO5A1'],
        ['HHEX','NUP98'],
        ['HHLA1','OC90'],
        ['HIP1','PDGFRB'],
        ['HIPK1','PAX5'],
        ['HIPK2','STAT6'],
        ['HIPK3','NRD1'],
        ['HIVEP3','SUPT6H'],
        ['HJURP','INPP4A'],
        ['HK1','MYPN'],
        ['HK1','TSPAN15'],
        ['HLF','TCF3'],
        ['HLTF','HPS3'],
        ['HM13','RLF'],
        ['HM13','TM9SF4'],
        ['HM13','TPX2'],
        ['HMBOX1','ZFAND3'],
        ['HMGA1','LAMA4'],
        ['HMGA1','RAD51L1'],
        ['HMGA2','DYRK2'],
        ['HMGA2','LEMD3'],
        ['HMGA2','LHFP'],
        ['HMGA2','LPP'],
        ['HMGA2','NFIB'],
        ['HMGA2','NUP107'],
        ['HMGA2','PTPRR'],
        ['HMGA2','RAD51L1'],
        ['HMGA2','WIF1'],
        ['HMGIC','LHFP'],
        ['HMGIC','LPP'],
        ['HMGIC','RAD51L1'],
        ['HMGN2P46','MYC'],
        ['HMGXB3','PPARGC1B'],
        ['HNF1B','LUC7L3'],
        ['HNRNPF','RASGEF1A'],
        ['HNRNPH1','MLLT10'],
        ['HOMEZ','MYH6'],
        ['HOMEZ','PRMT5'],
        ['HOOK3','RET'],
        ['HOPX','PDCL2'],
        ['HOXA10','NUP98'],
        ['HOXA10','TRB@'],
        ['HOXA11','NUP98'],
        ['HOXA11','TRB@'],
        ['HOXA13','NUP98'],
        ['HOXA9','MSI2'],
        ['HOXA9','NUP98'],
        ['HOXA9','TRB@'],
        ['HOXB3','NUP98'],
        ['HOXB4','NUP98'],
        ['HOXC10','WIBG'],
        ['HOXC11','NUP98'],
        ['HOXC13','NUP98'],
        ['HOXD11','NUP98'],
        ['HOXD13','NUP98'],
        ['HOXD3','NUP98'],
        ['HPRG1','LRRC6'],
        ['HPR','MRPS10'],
        ['HPR','RPS10'],
        ['HP','RSPO1'],
        ['HSD11B1','KCNH1'],
        ['HSP90AB1','PTCHD4'],
        ['HSP90AB1','SLC29A1'],
        ['HSP90AB1','SYNGAP1'],
#        ['HSPE1','PREI3'],
        ['HSPG2','TMCO4'],
        ['HTR2A','MED4'],
        ['HTRA3','TBC1D14'],
        ['ID4','IGH@'],
        ['IFI16','NOS1AP'],
        ['IFITM10','PPP1R12C'],
        ['IFT172','KRTCAP3'],
        ['IFT80','MLH1'],
        ['IGHG1','LHX4'],
        ['IGHG1','MYC'],
        ['IGH@','IGL@'], #???
        ['IGH@','IL3'],
        ['IGH@','IRF4'],
        ['IGH@','LAPTM5'],
        ['IGH@','LHX4'],
        ['IGH@','MAF'],
        ['IGH@','MAFB'],
        ['IGH@','MALT1'],
        ['IGH@','MUC1'],
        ['IGH@','MYC'],
        ['IGH@','NFKB2'],
        ['IGH@','PAFAH1B2'],
        ['IGH@','PAX5'],
        ['IGH@','PCSK7'],
        ['IGH@','RHOH'],
        ['IGH@','SPIB'],
        ['IGH@','TRA@'],
        ['IGH@','TRG@'],
        ['IGH@','WHSC1'],
        ['IGH@','WWOX'],
        ['IGK@','KDSR'],
        ['IGK@','MYC'],
        ['IGK@','PVT1'],
        ['IGKV3-20','RNA28S5'],
        ['IGL@','MAF'],
        ['IGL@','MYC'],
        ['IGL@','PVT1'],
        ['IGL@','WWOX'],
        ['IKBKB','TNPO1'],
        ['IKBKG','PLXNB3'],
        ['IKZF3','MED1'],
        ['IKZF3','NF1'],
        ['IKZF3','VAPB'],
        ['IL1RAP','FGF12'],
        ['IL22','VOPP1'],
        ['IL26','PPM1H'],
        ['IL27RA','SMARCA4'],
        ['IL2','TNFRSF17'],
        ['IL32','NAA60'],
        ['IMMT','SLC25A26'],
        ['INHBC','METTL1'],
        ['INHBC','TSFM'],
        ['INHBE','TSFM'],
        ['INTS1','PRKAR1B'],
        ['INTS2','TMEM49'],
        ['INTS2','ZNF652'],
        ['IP6K1','TRAIP'],
        ['IPO11','LRRC70'],
        ['IQCG','NUP98'],
        ['IQCJ','SCHIP1'],
        ['IRF2BP2','CDX1'],
        ['ITFG1','NETO2'],
        ['ITGA1','PDE4D'],
        ['ITGB5','SNX4'],
        ['ITGB8','ZCWPW1'],
        ['ITK','SYK'],
        ['ITM2B','RB1'],
        ['ITPKC','PPFIA3'],
        ['ITPRIPL1','YWHAQ'],
        ['IZUMO3','MLLT3'],
        ['JAK1','HIVEP3'],
        ['JAK1','RB1CC1'],
        ['JAK2','KIAA1432'],
        ['JAK2','NFE2'],
        ['JAK2','PAX5'],
        ['JAK2','PCM1'],
        ['JAK2','RPN1'],
        ['JAK2','SEC31A'],
        ['JAK2','SSBP2'],
        ['JAK2','STRN3'],
        ['JAK2','TEL'],
        ['JAM3','NCAPD3'],
        ['JARID1A','NUP98'],
        ['JAZF1','JJAZ1'],
        ['JAZF1','PHF1'],
        ['JAZF1','SUZ12'],
        ['JMJD1C','MICU1'],
        ['JMJD1C','NRBF2'],
        ['KANK1','PDGFRB'],
        ['KAT6A','LRP5'],
        ['KCTD20','SORBS2'],
        ['KDELR2','ROS1'],
        ['KDM2A','SYT12'],
        ['KDM4A','RASSF5'],
        ['KDM5A','NUP98'],
#        ['KDR','PDGFRA'],
        ['KDR','SH3BP2'],
        ['KHNYN','SDR39U1'],
        ['KIAA0146','MCM4'],
        ['KIAA0195','MGAT5B'],
        ['KIAA0515','PPAPDC3'],
        ['KIAA0642','TRPM8'],
        ['KIAA0756','NTRK1'],
        ['KIAA0833','MTOR'],
        ['KIAA0895','PDE1C'],
        ['KIAA0984','PPM1H'],
        ['KIAA0999','PPP2R1B'],
        ['KIAA1033','LGR5'],
        ['KIAA1199','ZYX'],
        ['KIAA1211','NMU'],
        ['KIAA1267','MBTD1'],
        ['KIAA1462','KIF5B'],
        ['KIAA1468','RET'],
        ['KIAA1509','PDGFRB'],
        ['KIAA1524','MLL'],
        ['KIAA1549L','RUNX1'],
        ['KIAA1618','TBC1D16'],
        ['KIAA1787','SENP3'],
        ['KIAA1797','MOBKL2B'],
        ['KIAA1967','SORBS3'],
        ['KIAA1984','TMEM141'],
        ['KIF16B','PCSK2'],
        ['KIF1B','UBE4B'],
        ['KIF21A','ZNF664'],
        ['KIF5A','OS9'],
        ['KIF5B','PDGFRA'],
        ['KIF5B','RET'],
        ['KIF5C','LYPD6B'],
        ['KIRREL3','RN7SL167P'],
        ['KIRREL3','RP11-721F8'],
        ['KIRREL3','RP11-831A10.2'],
        ['KIRREL3','VPS37C'],
        ['KIRREL','ZFYVE9'],
        ['KLHDC10','STAC'],
        ['KLK4','KLKP1'],
        ['KMO','RPS6KC1'],
        ['KPNA2','OSBPL9'],
        ['KRAS','SOX5'],
        ['KRAS','UBE2L3'],
        ['KRT14','RARA'],
        ['KRT86','MDM2'],
        ['KSR1','ODZ1'],
        ['KSR2','SETMAR'],
        ['KTN1','RET'],
        ['LAF4','MLL'],
        ['LAG3','MYH11'],
        ['PLAGL2','HCK'],
        ['LAMA3','RIOK3'],
        ['LAMP1','MCF2L'],
        ['LANCL2','PLEKHA7'],
        ['LANCL2','PSPH'],
        ['LANCL2','RP11-745C15.2'],
        ['LANCL2','SEPT14'],
        ['LANCL2','VOPP1'],
        ['LANCL2','ZNF713'],
        ['LARG','MLL'],
        ['LAS1L','OPHN1'],
        ['LASP1','MLL'],
        ['LASP1','TRPS1'],
        ['LASS6','USP32'],
        ['LCK','TRB@'],
        ['LDLRAD3','RICS'],
        ['LDLRAD3','TCP11L1'],
        ['LEDGF','NUP98'],
        ['LEKR1','TIPARP'],
        ['LEMD3','PPM1H'],
        ['LGALS12','SYNPO2L'],
        ['LGALS2','RBFOX2'],
        ['LGALS2','RBM9'],
        ['LGR5','NUP107'],
        ['LIFR','PLAG1'],
        ['LIN28A','SRGAP1'],
        ['LINC00478','NRIP1'],
        ['LMNA','NTRK1'],
        ['LMO1','TRA@'],
        ['LMO1','TRB@'],
        ['LMO1','TRD@'],
        ['LMO2','TRA@'],
        ['LMO2','TRB@'],
        ['LMO2','TRD@'],
        ['LNP1','NUP98'],
        ['LNX1','USP46'],
        ['LOC284100','PSMD3'],
        ['LPAR1','NAA15'],
        ['LPGAT1','RPS6KC1'],
        ['LPHN1','SUZ12'],
        ['LPP','MLL'],
        ['LPXN','PTPRJ'],
        ['LRBA','SH3D19'],
        ['LRCH3','RAB7A'],
        ['LRIG3','PIP4K2C'],
        ['LRIG3','ROS1'],
        ['LRIG3','TSFM'],
        ['LRP1','TMBIM4'],
        ['LRP1','XPO5'],
        ['LRP5','SLC22A24'],
        ['LRP5','TPCN2'],
        ['LRP8','TMEM48'],
        ['LRRC36','SLC7A6'],
        ['LRRC37B','NF1'],
        ['LRRC59','NEUROD2'],
        ['LRRFIP2','SUMF1'],
        ['LRRN2','NFASC'],
        ['LTBP3','RELA'],
        ['LXN','RPL21'],
        ['LY6H','PVT1'],
        ['LYL1','TRB@'],
        ['LYST','RPS6KC1'],
        ['MACF1','NOTCH2'],
        ['MACF1','RRAGC'],
        ['MACF','NOTCH2'],
        ['MACROD1','RUNX1'],
        ['MACROD1','VEGFB'],
        ['MAD1L1','RARS'],
        ['MAFG','NELL2'],
        ['MAGI1','STMN2'],
        ['MAGI3','NOTCH2'],
        ['MALAT1','TFEB'],
        ['MALT1','MAP4'],
        ['MALT1','SEC11C'],
        ['MAMDC1','SLC25A21'],
        ['MAML2','MECT1'],
        ['MAML2','MLL'],
        ['MAML2','MYB'],
        ['MAMLD1','YAP1'],
        ['MAN2A1','FER'],
        ['MAP2K7','SNAPC2'],
        ['MAP3K3','MYO15B'],
        ['MAP4K3','TMEM178'],
        ['MAP7','PERP'],
        ['MAPK4','RTTN'],
        ['MAPKBP1','MGA'],
        ['MAPRE1','MLL'],
        ['MARCH9','METTL1'],
        ['MARCH9','NOL10'],
        ['MARCH9','OS9'],
        ['MARK3','SMARCB1'],
        ['MARS','MON2'],
        ['MARS','PPM1H'],
        ['MAST1','NFIX'],
        ['MAST1','TADA2A'],
        ['MAST1','TADA2L'],
        ['MAST1','ZNF700'],
        ['MAST4','NDUFAF2'],
        ['MATK','ZFR2'],
        ['MATN2','PKHD1L1'],
        ['MBD1','RET'],
        ['MBIP','AXL'],
        ['MBOAT2','PRKCE'],
        ['MBTD1','CXORF67'],
        ['MBTPS2','YY2'],
        ['MCM5','TOM1'],
        ['MCM5','TRPM7'],
        ['MCM9','ROS1'],
        ['MDGA1','PTK7'],
        ['MDM1','RP11-745C15.2'],
        ['MDM2','PPM1H'],
        ['MDM2','VOPP1'],
        ['MDS1','RUNX1'],
        ['MEAF6','PHF1'],
        ['MEAF6','SCMH1'],
        ['MECOM','NRIP1'],
        ['MECOM','RPN1'],
        ['MECOM','RUNX1'],
        ['MECP2','TMLHE'],
        ['MED18','UBE4B'],
        ['MED1','STXBP4'],
        ['MED1','USP32'],
        ['MED1','WSB1'],
        ['MED6','RGS6'],
        ['MEF2D','ZDHHC5'],
        ['MELK','RNF38'],
        ['MESDC2','SENP1'],
#        ['MFGE8','HAPLN3'],
        ['MFSD2A','ZMPSTE24'],
        ['MGAT4C','PPP1R12A'],
        ['MICAL2','PPAP2A'],
        ['MICAL3','XBP1'],
        ['MIDN','STK11'],
        ['MIER2','RSRC2'],
        ['MIPOL1','NPAS3'],
        ['MIPOL1','SKIL'],
        ['MIR143HG','NOTCH1'],
        ['MIR143HG','NOTCH2'],
        ['MIR143HG','NOTCH3'],
        ['MIR143','NOTCH1'],
        ['MIR143','NOTCH2'],
        ['MIR143','NOTCH3'],
        ['MIXL1','PARP1'],
        ['MKL1','NIPA1'],
        ['MKL1','RBM15'],
        ['MKLN1','SCRN1'],
        ['MKRN1','BRAF'],
        ['MLF1','NPM1'],
        ['MLL3','CHGB'],
        ['MLL','FNBP1'],
        ['MLL','MLLT1'],
        ['MLL','MLLT10'],
        ['MLL','MLLT11'],
        ['MLL','MLLT3'],
        ['MLL','MLLT4'],
        ['MLL','MLLT6'],
        ['MLL','MYO1F'],
        ['MLL','NCKIPSD'],
        ['MLL','NEBL'],
        ['MLL','NRIP3'],
        ['MLL','NUP98'],
        ['MLL','PDS5A'],
        ['MLL','PICALM'],
        ['MLL','PNUTL1'],
        ['MLL','RARA'],
        ['MLL','RREB1'],
        ['MLL','SARNP'],
        ['MLL','SEPT11'],
        ['MLL','SEPT2'],
        ['MLL','SEPT5'],
        ['MLL','SEPT6'],
        ['MLL','SEPT9'],
        ['MLL','SMAP1'],
        ['MLL','SNAPC3'],
        ['MLL','SORBS2'],
        ['MLLT10','NAP1L1'],
        ['MLLT10','PICALM'],
        ['MLLT10','PPP2R1B'],
        ['MLLT6','TEM7'],
        ['MLLT7','PAX3'],
        ['MLL','TET1'],
        ['MLL','TIRAP'],
        ['MLL','TNRC18'],
        ['MLL','UBE4A'],
        ['MLL','VAV'],
        ['MLL','ZFYVE19'],
        ['MMP20','TMEM123'],
        ['MN1','TEL'],
        ['MNX1','MYB'],
        ['MOGAT2','UVRAG'],
        ['MON2','SLC16A7'],
        ['MORN1','SLC6A9'],
        ['MOZ','TIF2'],
        ['MPND','RAB8A'],
        ['MPRIP','NTRK1'],
        ['MPRIP','UBB'],
        ['MRC2','MAP3K3'],
        ['MRC2','RND2'],
        ['MRPL27','SPAG9'],
        ['MRPL45','TRPC4AP'],
        ['MSH5','NFKBIL1'],
        ['MSI2','NEK8'],
        ['MSL2L1','SFRS10'],
        ['MSL2','STAG1'],
        ['MSLN','WDR90'],
        ['MTAP','C9ORF92'],
        ['MTAP','PCDH7'],
        ['MTBP','SAMD12'],
        ['MTCP1','TRA@'],
        ['MTCP1','TRB@'],
        ['MTF1','SF3A3'],
        ['MTMR4','TANC1'],
        ['MTOR','TP53BP1'],
        ['MTR','RYR2'],
        ['MTS1','MTS2'],
        ['MTSS1','TATDN1'],
        ['MYB','NFIB'],
        ['MYBPC1','PDZRN4'],
        ['MYB','PCDHGA1'],
        ['MYB','QKI'],
        ['MYB','TRB@'],
        ['MYCL1','RLF'],
        ['MYCL1','SMAP2'],
        ['MYC','PVT1'],
        ['MYC','TRA@'],
        ['MYC','ZBTB5'],
        ['MYC','ZCCHC7'],
        ['MYH7','PVT1'],
        ['MYH9','MYO18B'],
        ['MYH9','USP6'],
        ['MYL6B','VWA3A'],
        ['MYO18A','PDGFRB'],
        ['MYO18B','UBE2R2'],
        ['MYO19','SKA2'],
        ['MYO19','TRIM37'],
        ['MYO1A','XPO5'],
        ['MYO5C','TNFAIP8L3'],
        ['MYO7A','SESN3'],
        ['MYO9B','RAB22A'],
        ['MYOF','TNKS2'],
        ['MYST3','NCOA2'],
        ['MYST3','NCOA3'],
        ['NAA30','TERT'],
        ['NAB2','STAT6'],
        ['NABP1','RARA'],
        ['NACA','RPL41'],
        ['NACC2','NTRK2'],
        ['NADSYN1','SUV420H1'],
        ['NAIP','OCLN'],
        ['NARG1','NDUFC1'],
        ['NAV1','NTRK2'],
        ['NBR1','WSB1'],
        ['NCAPD2','PRPF3'],
        ['NCAPD3','VPS26B'],
        ['NCBP1','XPA'],
        ['NCOA1','PAX3'],
        ['NCOA2','PAX3'],
        ['NCOA2','ZNF704'],
        ['NCOA4','RET'],
        ['NCOA6','PIGU'],
        ['NCOR2','SCARB1'],
        ['NDE1','PDGFRB'],
        ['NDRG1','PVT1'],
        ['NDUFB8','SEC31B'],
        ['NDUFB9','PGCP'],
        ['NECAB2','OSGIN1'],
        ['NEDD4L','NPAS2'],
        ['NEDD4L','PRPH2'],
        ['NEGR1','ZRANB2'],
        ['NEK1','RUNX2'],
        ['NEK6','RXRA'],
        ['NELL2','OS9'],
        ['NELL2','TMEM117'],
        ['NF1','NLE1'],
        ['NF1','PSMD11'],
        ['NFASC','NTRK1'],
        ['NFASC','PRELP'],
        ['NFASC','RTN3'],
        ['NFASC','SOX13'],
        ['NFATC3','CPNE2'],
        ['NFE2','R3HDM2'],
        ['NFIA','RNLS'],
        ['NFKBIL2','RAE1'],
        ['NFS1','PREX1'],
        ['NFYA','TDRG1'],
        ['NGFR','SPAG9'],
        ['NICN1','RASA2'],
        ['NIN','PDGFRB'],
        ['NKAIN2','SENP6'],
        ['NKIRAS1','RAF1'],
#        ['NKRF','SEPT6'],
        ['NKX2-5','TRD@'],
        ['NLK','NF1'],
        ['NLRP8','PPP2R1A'],
        ['NOC4L','SDS'],
        ['NOL4','PVT1'],
        ['NOL5A','TMC2'],
        ['NONO','TFE3'],
        ['NOP2','TCF3'],
        ['NOTCH1','NUP214'],
        ['NOTCH1','SEC16A'],
        ['NOTCH1','SNHG7'],
        ['NOTCH1','TCRB@'],
        ['NOTCH1','TRB@'],
        ['NOTCH2','SEC22B'],
        ['NOTCH2','TMEM150C'],
        ['NOTCH3','VIM'],
        ['NPEPPS','OSBPL9'],
        ['NPEPPS','TBC1D3'],
        ['NPHS1','SIRT2'],
        ['NPM1','RARA'],
        ['NPM','ALK'],
        ['NPSR1','POU6F2'],
        ['NR4A3','RBP56'],
        ['NR4A3','TAF15'],
        ['NR4A3','TAFII68'],
        ['NR4A3','TCF12'],
        ['NR4A3','TFG'],
        ['NR6A1','OBP2B'],
        ['NRG1','ERBB'],
        ['NRG1','ODZ4'],
        ['NRG1','SLC3A2'],
        ['NRIP1','TIAM1'],
        ['NRIP1','UHRF1'],
        ['NSD1','NUP98'],
        ['NSD1','STIM1'],
        ['NSD3','NUP98'],
        ['NSL1','VASH2'],
        ['NSMCE2','PVT1'],
        ['NSMCE2','SQLE'],
        ['NTNG2','NUP153'],
        ['NTRK1','RABGAP1L'],
        ['NTRK1','RET'],
        ['NTRK1','TFG'],
        ['NTRK1','TPM3'],
        ['NTRK1','TPR'],
        ['NTRK2','QKI'],
        ['NUCKS1','PM20D1'],
        ['NUDCD1','SYBU'],
        ['NUMA1','RARA'],
        ['NUP107','PDZRN4'],
        ['NUP107','TSFM'],
        ['NUP188','SPTAN1'],
        ['NUP214','ABL1'],
        ['NUP214','SET'],
        ['NUP214','SQSTM1'],
        ['NUP214','XKR3'],
        ['NUP98','PHF23'],
        ['NUP98','POU1F1'],
        ['NUP98','PRRX1'],
        ['NUP98','PRRX2'],
        ['NUP98','PSIP1'],
        ['NUP98','RAP1GDS1'],
        ['NUP98','RARG'],
        ['NUP98','SETBP1'],
        ['NUP98','TOP1'],
        ['NUP98','TOP2B'],
        ['NUP98','WHSC1L1'],
        ['OBFC2A','RARA'],
        ['OBSCN','RNF187'],
        ['ODF1','STK3'],
        ['ODZ2','SRGAP1'],
        ['ODZ4','PACS1'],
        ['ODZ4','SAPS3'],
        ['OLIG2','TRA@'],
        ['OLR1','XIAP'],
        ['OMD','USP6'],
        ['OPA3','SIRT2'],
        ['OPRD1','UNQ2998'],
        ['OPRD1','ZMYM4'],
        ['OPRL1','SGPP2'],
        ['ORC2L','SF3B1'],
        ['OS9','SLC35E3'],
        ['OSBPL9','ZNF326'],
        ['OSGIN2','RIPK2'],
        ['OSTBETA','RASL12'],
        ['OTUB1','SHANK2'],
        ['P11','RAPGEF3'],
        ['P2RX3','RTN4RL2'],
        ['PACS1','RBM14'],
        ['PAM','ST8SIA4'],
        ['PANK1','PPP2R2D'],
        ['PATL1','TECTA'],
        ['PAX3','MAML3'],
        ['PAX5','PML'],
        ['PAX5','POM121'],
        ['PAX5','SLCO1B3'],
        ['PAX5','ZNF521'],
        ['PAX7','VPS13D'],
        ['PAX8','PPARG'],
        ['PBX1','TCF3'],
        ['PBX4','SLC44A2'],
        ['PCBP2','UHRF1BP1L'],
        ['PCDHGC3','QKI'],
        ['PCDHGC4','QKI'],
        ['PCGF2','TAOK1'],
        ['PCM1','RET'],
        ['PCMT1','LATS1'],
        ['PDAP1','SMURF1'],
        ['PDE1C','ZIM2'],
        ['PDE4DIP','PDGFRB'],
        ['PDE4D','PPP2R2B'],
        ['PDE8B','UIMC1'],
        ['PDGFRA','SCAF11'],
        ['PDGFRA','STRN'],
        ['PDGFRB','PRKG2'],
        ['PDGFRB','RABEP1'],
        ['PDGFRB','SPECC1'],
        ['PDGFRB','SPTBN1'],
        ['PDGFRB','TP53BP1'],
        ['PDGFRB','TPM3'],
        ['PDGFRB','TRIP11'],
        ['PDGFRB','WDR48'],
        ['PDHX','PVT1'],
        ['PDIA5','RAB6B'],
        ['PDLIM4','RAD50'],
        ['PDLIM5','TCEB1'],
        ['PDZRN4','SLC35E3'],
        ['PEBP4','RHOBTB2'],
        ['PEPD','RHPN2'],
        ['PERLD1','PPM1D'],
        ['PERLD1','SGMS2'],
        ['PFKFB3','RGS10'],
        ['PFKM','SLC11A2'],
        ['PHACTR4','RCC1'],
        ['PHF15','UBE2B'],
        ['PHF20L1','SAMD12'],
        ['PHOSPHO1','SPAG9'],
        ['PHTF2','PPP3CB'],
        ['PICALM','RCC1'],
        ['PICALM','TEX10'],
        ['PIGG','SPINK2'],
        ['PIK3C2A','TEAD1'],
        ['PIK3C2B','PLEKHA6'],
        ['PIK3C3','RPRD1A'],
        ['PIK3C3','TWSG1'],
        ['PIK3CA','USP13'],
        ['PIK3CD','RERE'],
        ['PIK3R2','USP8'],
        ['PIM3','SCO2'],
        ['PION','STYXL1'],
        ['PIP4K2B','RAD51C'],
        ['PIP4K2C','R3HDM2'],
        ['PIP5K2B','RAD51C'],
        ['PIPOX','PPP1R1B'],
        ['PKD1','UBE2J2'],
        ['PKHD1L1','PTK2'],
        ['PKIA','RARA'],
        ['PLA2G6','CRYBB1'],
        ['PLAG1','RAD51L1'],
        ['PLAG1','TCEA1'],
        ['PLCG1','TOP1'],
        ['PLDN','SQRDL'],
        ['PLEKHD1','SLC39A9'],
        ['PLEKHM2','TMEM51'],
        ['PLEKHO1','VPS45'],
        ['PLSCR1','SLC25A36'],
        ['PLZF','RARA'],
        ['PML','RARA'],
        ['POLD1','PRR12'],
        ['POLR2A','WRAP53'],
        ['POLR2K','VPS13B'],
        ['POLR3GL','PROM2'],
        ['POMGNT1','TSPAN1'],
        ['PPA2','TBCK'],
        ['PPAPDC1A','PVT1'],
        ['PPIG','ZNF430'],
        ['PPM1H','TBC1D30'],
        ['PPP1CB','YPEL5'],
        ['PPP1R12A','SEPT10'],
        ['PPP1R12B','SNX27'],
        ['PPP1R13L','ZNF541'],
        ['PPP1R1B','PSMD3'],
        ['PPP1R1B','STARD3'],
        ['PPP1R9A','WBSCR17'],
        ['PPP2R2B','YTHDC2'],
        ['PPP3R1','TTC27'],
        ['PPP5D1','ZNF83'],
        ['PPP6R2','SPECC1L'],
        ['PPT1','SPP1'],
        ['PRAME','RPTOR'],
        ['PRCC','TFE3'],
        ['PRDM16','PSMD2'],
        ['PRDM16','RPN1'],
        ['PRDM16','RUNX1'],
        ['PRDM16','SKI'],
        ['PRDM7','RUNX1'],
        ['PRDX1','TESK2'],
        ['PRDX4','RUNX1'],
        ['PREX1','SLC9A8'],
        ['PRG2','SLC43A3'],
        ['PRICKLE2','SULF2'],
        ['PRKAG2','RHEB'],
        ['PRKAG2','ST7'],
        ['PRKAR1A','RARA'],
        ['PRKAR1A','RET'],
        ['PRKCB','TNRC6A'],
        ['PRKCH','VWA2'],
        ['PRKCZ','SKI'],
        ['PRMT2','RCAN1'],
        ['PRMT7','SLC7A6'],
        ['PRPSAP1','PSCD1'],
        ['PRR11','WDR68'],
        ['PRRC1','RUNX1'],
        ['PRSS3','UBE2R2'],
        ['PSF','TFE3'],
        ['PSKH1','TSNAXIP1'],
        ['PSMB5','RBM23'],
        ['PSMB8','TAP1'],
        ['PSMD8','SIPA1L3'],
        ['PTBP2','UBIAD1'],
        ['PTC3','RET'],
        ['PTCH1','FAM120AOS'],
        ['PTCH1','RET'],
        ['PTEN','COL17A1'],
        ['PTGES3','PTPRB'],
        ['PTK2','STK3'],
        ['PTK2','THOC2'],
        ['PTK6','ZNF142'],
        ['PTN','DGKI'],
        ['PTPN2','UBLCP1'],
        ['PTPRD','LRMP'],
        ['PTPRF','ST3GAL3'],
        ['PTPRG','TEX14'],
        ['PTPRK','RSPO3'],
        ['PTPRR','SRGAP1'],
        ['PTPRZ1','MET'],
        ['PUM1','SAPS3'],
        ['PUM1','TRERF1'],
        ['PVRL2','TRA@'],
        ['PVT1','FGFR2'],
        ['PVT1','SLC1A2'],
        ['PVT1','SLC7A7'],
        ['PVT1','TRD@'],
        ['QKI','NTRK2'],
        ['QKI','RAF1'],
        ['R3HDM2','SORBS2'],
        ['R3HDM2','TSFM'],
        ['R3HDM2','XRCC6BP1'],
        ['RAB20','VWC2'],
        ['RAB22A','TTC3'],
        ['RAB2A','SNX9'],
        ['RAB2','NRG1'],
        ['RAB3IP','SRGAP1'],
        ['RAB6IP2','RET'],
        ['RAD21','UTP23'],
        ['RAD23A','ZNF562'],
        ['RAD54L2','VPRBP'],
        ['RAD9A','SHANK2'],
        ['RAE1','STX16'],
        ['RAE1','ZMYND8'],
        ['RAF1','RBM35A'],
        ['RAF1','SRGAP3'],
        ['RALA','ZNF610'],
        ['RALY','SYNGAP1'],
        ['RANBP17','TRD@'],
        ['RANBP2','ALK'],
        ['RAP1B','TMBIM4'],
        ['RAPGEF3','SLC48A1'],
        ['RARA','STAT5B'],
        ['RARA','ZBTB16'],
        ['RASGRF2','RNF145'],
        ['RAX','SMAD4'],
        ['RB1','RFX3'],
        ['RB1','SLC15A2'],
        ['RBFOX1','VASN'],
        ['RBM12B','MMP16'],
#        ['RBM14','RBM4'],
        ['RBM6','SRGAP1'],
        ['RBMS1','SEMA4C'],
        ['RBPMS','NRG1'],
        ['RC3H2','RGS3'],
        ['RCC17','TFE3'],
        ['RCC1','UBE2D2'],
        ['RDH11','VTI1B'],
        ['RDM1','TANC2'],
        ['RELA','ZMYND8'],
        ['RER1','ZC3H7B'],
        ['RERE','SLC2A5'],
        ['RERE','SLC9A1'],
        ['RET','TRIM24'],
        ['RET','TRIM27'],
        ['RET','TRIM33'],
        ['RFT1','UQCRC2'],
        ['RFX5','SELENBP1'],
        ['RGNEF','ZFP62'],
        ['RGS17','TBL1XR1'],
        ['RGS3','SLC31A2'],
        ['RGS7','SMYD3'],
        ['RHOA','WWTR1'],
        ['RHOC','RPS6KA1'],
        ['RIMS2','STK3'],
        ['RLF','SMAP2'],
        ['RLF','UBE2J2'],
        ['RMI1','STX17'],
        ['RMND5B','SFXN1'],
        ['RNF111','TCF12'],
        ['RNF121','SFRS2IP'],
        ['RNF130','BRAF'],
        ['RNF19B','YARS'],
        ['RNF213','SLC26A11'],
        ['RNFT1','TRIM37'],
        ['ROR1','ZNF362'],
        ['ROS1','CCDC6'],
        ['ROS1','SDC4'],
        ['ROS1','SLC34A2'],
        ['ROS1','TPM3'],
        ['RP11-57H14.3','TCF7L2'],
        ['RP11-745C15.2','SEC61G'],
        ['RP11-745C15.2','SLC35E3'],
        ['RP11-745C15.2','ZNF713'],
        ['RPL14','SLC7A11'],
        ['RPL22P1','RUNX1'],
        ['RPL36','TTYH1'],
        ['RPL39L','UBXN7'],
        ['RPS6KB1','SNF8'],
        ['RPS6KB1','TMEM49'],
        ['RPS6KB1','VMP1'],
        ['RPTOR','TULP4'],
        ['RTF1','TYRO3'],
        ['RUFY1','TMEM178B'],
        ['RUNX1','RUNX1T1'],
        ['RUNX1','SH3D19'],
        ['RUNX1','SV2B'],
        ['RUNX1','TRPS1'],
        ['RUNX1','USP42'],
        ['RUNX1','YTHDF2'],
        ['RUNX1','ZFPM2'],
        ['RUNX1','ZNF687'],
#        ['RWDD3','TMEM56'],
        ['RYR2','USH2A'],
        ['SACS','SGCG'],
        ['SCAF1','TRAPPC6A'],
        ['SCAI','ZBTB34'],
        ['SCAMP2','WDR72'],
        ['SCAPER','TM6SF1'],
        ['SCL','TRD@'],
#        ['SCNN1A','TNFRSF1A'],
        ['SDC4P','SEC14L4'],
        ['SDC4','SPCS1'],
        ['SEMA6B','SLC27A1'],
        ['SEPT9','ABL1'],
        ['SERPINE1','FOSB'],
        ['SERPINF2','WDR81'],
        ['SET','NUP214'],
        ['SFPQ','TFE3'],
        ['SGTA','SLC39A3'],
        ['SH3BP5','VGLL4'],
#        ['SIDT2','TAGLN'],
        ['SIL','TAL1'],
        ['SIRT2','ZNF45'],
        ['SKAP1','THRA'],
        ['SKIL','TMPRSS2'],
        ['SKI','SSU72'],
        ['SKP2','SLC1A3'],
        ['SLAMF1','UVRAG'],
        ['SLC16A7','MUCL1'],
        ['SLC22A23','TNFRSF21'],
        ['SLC25A32','UBR5'],
        ['SLC26A10','TSFM'],
        ['SLC34A2','ROS1'],
        ['SLC35E3','YEATS4'],
        ['SLC45A2','AMACR'],
        ['SLC4A1AP','SUPT7L'],
        ['SMARCE1','TMEM99'],
        ['SMEK1','SRM'],
        ['SMG5','TMEM79'],
        ['SMYD3','XRN1'],
        ['SMYD3','ZNF670'],
        ['SNTB2','VPS4A'],
        ['SNX9','CYP2C19'],
        ['SORCS2','TADA2B'],
        ['SORD','SPG11'],
        ['SPOCK1','TBC1D9B'],
        ['SPTAN1','TRAF4'],
        ['SQSTM1','NUP214'],
        ['SRGAP1','MSRB3'],
        ['SRP68','URM1'],
        ['SS18L1','SSX1'],
        ['SS18','SSX'],
        ['SS18','SSX1'],
        ['SS18','SSX2'],
        ['SS18','SSX4'],
        ['SSBP1','WEE2'],
        ['SSBP3','TMEM48'],
        ['SSX1','SYT'],
        ['SSX2','SYT'],
        ['ST6GAL1','WHSC1'],
        ['ST7','CTTNBP2'],
        ['STAG1','STXBP5L'],
        ['STARD3','TAC4'],
        ['STAU1','TOP1'],
        ['STIL','TAL1'],
        ['STK40','THRAP3'],
        ['STRN4','TECR'],
        ['STRN','ALK'],
        ['SULF2','UBE2V1'],
        ['SUSP1','TCBA1'],
        ['SYNRG','TOB1'],
        ['SYT','SSX'],
        ['TAF15','ZNF384'],
        ['TAL1','TCTA'],
        ['TAL1','TRB@'],
        ['TAL1','TRD@'],
        ['TAL2','TRB@'],
        ['TATDN1','DEPTOR'],
        ['TBC1D22A','TP73'],
        ['TBC1D31','ZNF704'],
        ['TBC1D3','USP32'],
        ['TBCB','UBE4B'],
        ['TBL1XR1','TP63'],
        ['TCF3','PBX1'],
        ['TCF3','TFPT'],
        ['TCF3','ZNF384'],
        ['TCF7L1','KIF1B'],
        ['TCF7L2','VTI1A'],
        ['TCL1A','TRA@'],
        ['TCL1A','TRB@'],
        ['TCL1A','TRD@'],
        ['TEC','TFG'],
        ['TFE3','YAP1'],
        ['TFEB','TRERF1'],
        ['TGFB1','SAE1'],
        ['THADA','MTA3'],
        ['THRAP3','USP6'],
        ['TLN1','TMEM8B'],
        ['TLX1','TRA@'],
        ['TLX1','TRB@'],
        ['TLX1','TRD@'],
        ['TLX3','TRD@'],
        ['TMBIM4','MSRB3'],
        ['TMCO1','UCK2'],
        ['TMED10','ZNF252'],
        ['TMEM178','MAP4K3'],
        ['TMEM184B','VPS13C'],
        ['TMEM19','TSPAN8'],
        ['TMEM49','TRIM37'],
        ['TMEM91','ZNF550'],
        ['TNFSF11','APLP2'],
        ['TNK1','ZBTB7A'],
        ['TPM3','TPR'],
        ['TPT1','AADAT'],
        ['TRAPPC10','USP25'],
        ['TRA@','TRB@'],
        ['TRDN','UBR4'],
        ['TRIM24','RET'],
        ['TRIM27','RET'],
        ['TRIM33','RET'],
        ['TRMT11','GRIK2'],
        ['TRMT1L','XPR1'],
        ['TRUB2','VAV2'],
        ['TSEN54','UNC84A'],
        ['TSHZ2','ZNF251'],
        ['TTLL3','ZC3H4'],
        ['TUBGCP2','ZNF511'],
        ['TXNDC11','ZC3H7A'],
        ['UBA5','MRAS'],
        ['UBQLN4','ZSWIM4'],
        ['UBR4','ZFP37'],
        ['UBR5','ZNF423'],
        ['USP10','ZDHHC7'],
        ['USP15','CNTN1'],
        ['USP31','WNK1'],
        ['USP33','ZFYVE9'],
        ['USP54','ZMIZ1'],
        ['VHL','BRK1'],
        ['VPS18','ZFYVE19'],
        ['VSTM2A','ZNF713'],
        ['WASF2','FGR'],
        ['WDR67','ZNF704'],
        ['WRN','NRG1'],
        ['WWTR1','CAMTA1'],
        ['WWTR1','FOSB'],
        ['XRCC6BP1','YEATS4'],
        ['YAP1','TFE3'],
        ['ZC3H7B','BCOR'],
        ['ZFP36','FOSB'],
        ['ZMIZ1','MAT1A'],
        ['ZNF236','ZNF516'],
#        ['ZNF761','ZNF813'],
        ['CREB3L2','PPARG'],
        ['PAX8','PPARG'],
        ['RET','PTC'],
        ['EML4','ALK'],
        ['PDS5A','KLB'],
        ['METAP2','PIK3C2G'],
        ['SLC45A3','UBE3A'],
        ['CCDC112','CDC25C'],
        ['BPTF','METTL2A'],
        ['EHMT1','ANAPC2'],
        ['ZNF618','MUSK'],
        ['FARS2','BMP6'],
        ['RPS4XP19','CPT1A'],
        ['BCOR','CCNB3'],
        ['SEPT9','ABL1'],
        ['BCR','ABL1'],
        ['ETV6','ABL1'],
        ['EML1','ABL1'],
        ['NUP214','ABL1'],
        ['ZMIZ1','ABL1'],
        ['RCSD1','ABL1'],
        ['SFPQ','ABL1'],
        ['FOXP1','ABL1'],
        ['SNX2','ABL1'],
#        ['ADCK4','NUMBL'],
        ['ASH1L','C1ORF61'],
        ['BCAN','NTRK1'],
        ['CAND1','EGFR'],
        ['EGFR','SEPT14'],
        ['EGFR','VOPP1'],
        ['EIF4H','GTF2I'],
        ['FGFR3','TACC3'],
        ['FUS','CREB3L2'],
        ['LANCL2','SEPT14'],
        ['MAPK1','FAM119B'],
        ['MAPK1','METTL21B'],
        ['PPP2R2B','CCT3'],
        ['PPP2RA','CHEK2'],
        ['SEC61G','EGFR'],
        ['SETD1B','GTF2H3'],
        ['TBC1D14','HTRA3'],
        ['TDRD3','ESD'],
        ['TFG','GPR128'],
        ['TRAF1','ALK'],
        ['VOPP1','IL22'],
        ['YEATS4','XRCC6BP1'],
        ['DCBLD2','STXBP5L'],
        ['LINC01291','POLE4'],
        ['KATNAL1','ZC3H13'],
        ['AAK1','C2ORF42'],
        ['AAK1','RPL36A'],
        ['AAK1','WFDC10B'],
        ['AAK1','WFDC13'],
        ['ABL1','ADAMTSL2'],
        ['ABL1','PRDM12'],
        ['ABRACL','MAP3K5'],
        ['ABR','CLUH'],
        ['ABR','GAS7'],
        ['ABR','KCNK1'],
        ['ABR','STAP2'],
        ['ABR','YWHAE'],
        ['ACPP','AXL'],
        ['ACTB','OXSR1'],
        ['ACVR1B','PGC'],
        ['ACVR1','NFATC1'],
        ['ACVR2A','AKT3'],
        ['ACVR2A','CASP8'],
        ['ACVR2A','SUMO1'],
        ['ADCK1','KCNQ2'],
        ['ADCK2','TBXAS1'],
        ['ADCK3','EPHX1'],
        ['ADCK4','AKAP8'],
        ['ADCY9','PRKCB'],
        ['ADK','PI4K2A'],
        ['ADRBK1','BAIAP2'],
        ['ADRBK1','CHGA'],
        ['ADRBK1','POLD4'],
        ['ADRBK2','AP1B1'],
        ['ADRBK2','EP300'],
        ['ADRBK2','RHBDL3'],
        ['ADRBK2','SF3A1'],
        ['AFAP1','NTRK2'],
        ['AFF3','MAP4K4'],
        ['AGGF1','RAF1'],
        ['AGK','BRAF'],
        ['AGO2','PTK2'],
        ['AHNAK','RPS6KA4'],
        ['AKAP13','RET'],
        ['AKAP6','PRKD1'],
        ['AKT1','PGC'],
        ['AKT2','CXCL11'],
        ['AKT2','ART3'],
        ['AKT2','SRRM5'],
        ['AKT2','ZNF576'],
        ['AKT2','YIF1B'],
        ['ANK1','FGFR1'],
        ['ANK2','ALPK1'],
        ['ANKRD28','FLT3'],
        ['ANXA4','PKN1'],
        ['AP3B1','BRAF'],
        ['APOPT1','MARK3'],
        ['APPL2','CIT'],
        ['ARHGEF10L','PAK4'],
        ['ARHGEF18','INSR'],
        ['ARID1A','PRKCZ'],
        ['ARID1A','RPS6KA1'],
        ['ARPC1B','TRRAP'],
        ['ARSG','MAP2K6'],
        ['ATG7','BRAF'],
        ['ATP11A','ULK4'],
        ['ATP1B3','GRK7'],
        ['ATP1B3','PRKAA2'],
        ['ATR','DBR1'],
        ['AURKA','SOGA1'],
        ['AXL','ZNF565'],
        ['B3GALTL','STK33'],
        ['B4GALT2','JAK1'],
        ['BAG4','FGFR1'],
        ['BAIAP2L1','MET'],
        ['BAZ1A','NKX2-1'],
        ['BAZ1A','RNF115'],
        ['BAZ1A','SFTA3'],
        ['BAZ1B','ABHD11'],
        ['BAZ2A','ACVR1B'],
        ['BCAS3','PRKAA2'],
        ['BCKDHB','TTK'],
        ['BCL2L11','BRAF'],
        ['BCR','ANKRD28'],
        ['BCR','MRVI1'],
        ['BCR','MYH11'],
        ['BCR','PPIL2'],
        ['BCR','PTPRD'],
        ['BCR','TOM1'],
        ['BCR','UPB1'],
        ['BLK','ACOT11'],
        ['BMP2K','SLC4A4'],
        ['BMPR1A','C10ORF11'],
        ['BMPR1A','ZYG11A'],
        ['BMPR1B','ETV1'],
        ['BMPR1B','NPTX1'],
        ['BMPR1B','NRG1'],
        ['BMPR1B','PDLIM5'],
        ['BMPR1B','ZMIZ1'],
        ['BMPR2','CADM2'],
        ['BMPR2','MARCH4'],
        ['BMPR2','SPATS2L'],
        ['BMPR2','WDTC1'],
        ['BRD2','PIGR'],
        ['BRD3','PIP5KL1'],
        ['BRSK1','COX6B1'],
        ['BRSK1','HSPBP1'],
        ['BRWD1','DYRK1A'],
        ['BRWD1','LMTK3'],
        ['BUB1B','CCDC170'],
        ['BUB1B','PCM1'],
        ['C11ORF80','MKNK1'],
        ['C12ORF45','CDK7'],
        ['C19ORF10','MAP2K3'],
        ['C19ORF47','MAP3K10'],
        ['C1S','MAP3K13'],
        ['LPCAT3','MAP3K13'],
        ['C5ORF22','MAP2K5'],
        ['C6ORF211','PDPK1'],
        ['C8ORF34','MET'],
        ['CAMK1D','ARL3'],
        ['CAMK1D','FAM188A'],
        ['CAMK1D','FUBP1'],
        ['CAMK1D','TSPAN18'],
        ['CAMK2B','SPIDR'],
        ['CAMK2D','ANK2'],
        ['CAMK2D','TLL2'],
        ['CAMK2G','NDUFA13'],
        ['CAMKK2','ANAPC5'],
        ['CAMKK2','DIP2B'],
        ['CAMKK2','HPD'],
        ['CAMKK2','KDM2B'],
        ['CAMKK2','NR2C1'],
        ['CAMKK2','PMCH'],
        ['CAMTA2','LCK'],
        ['CASK','SQRDL'],
        ['CASK','TM9SF2'],
        ['CASZ1','MTOR'],
        ['CASZ1','PRKD2'],
        ['CCDC6','RET'],
        ['CCSER1','BMP2K'],
        ['CD36','ITK'],
        ['CD74','CAMK2A'],
        ['CD74','ROS1'],
        ['CDC27','BRAF'],
        ['CDC42BPA','WWOX'],
        ['CDC42BPB','C14ORF182'],
        ['CDC42BPB','SYNJ2BP'],
        ['CDC42BPB','ZFYVE1'],
        ['CDK11A','GNB1'],
        ['CDK12','CACNB1'],
        ['CDK12','CDC6'],
        ['CDK12','CLCN4'],
        ['CDK12','FBXL20'],
        ['CDK12','SMG6'],
        ['CDK13','C7ORF10'],
        ['CDK13','DIP2C'],
        ['CDK13','PDE1C'],
        ['CDK13','POU6F2'],
        ['CDK13','TAX1BP1'],
        ['CDK14','TFEC'],
        ['CDK19','AMD1'],
        ['CDK19','LYZ'],
        ['CDK19','PRDM1'],
        ['CDK1','WDR11'],
        ['CDK2','PAN2'],
        ['CDK6','AKAP9'],
        ['CDK6','C11ORF48'],
        ['CDK6','METTL12'],
        ['CDK6','FN1'],
        ['CDK6','GATAD1'],
        ['CDK6','HEPACAM2'],
        ['CDK6','PIM3'],
        ['CDK6','PPM1H'],
        ['CDK6','RPSA'],
        ['CDK6','STXBP6'],
        ['CDK6','TAF1D'],
        ['CDK6','TCP1'],
        ['CDK7','CCNB1'],
        ['CDK8','GTF2F2'],
        ['CDK8','IKZF3'],
        ['CDKL1','TSEN2'],
        ['CDKL2','CXCL11'],
        ['CDKL2','ART3'],
        ['CEP170','PRKACB'],
        ['CEP85L','ROS1'],
        ['CHDC2','MAP3K8'],
        ['CHEK1','EXOC6'],
        ['CHEK1','NTM'],
        ['CHGA','MAPKAPK2'],
        ['CIT','FAM222A'],
        ['CLCN6','RAF1'],
        ['CLK2','CD244'],
        ['CLK2','MARS'],
        ['CLK2','PPP1R12B'],
        ['CLTC','ROS1'],
        ['COG6','MAPK8'],
        ['NT5DC1','HIPK1'],
        ['COL10A1','HIPK1'],
        ['COL1A1','PIKFYVE'],
        ['COMMD9','CDKL2'],
        ['CPD','ERBB2'],
        ['CPM','PRKAA2'],
        ['CPNE4','STK36'],
        ['CSF1R','CAP2'],
        ['CSF1R','PGC'],
        ['CSK','C15ORF27'],
        ['CSNK1A1','PDE6A'],
        ['CSNK1A1','SCGB3A2'],
        ['CSNK1D','ASPSCR1'],
        ['CSNK1D','SCPEP1'],
        ['CSNK1D','SECTM1'],
        ['CSNK1D','ST6GALNAC1'],
        ['CSNK1E','DMC1'],
        ['CSNK1G1','AP4E1'],
        ['CSNK1G1','INTS2'],
        ['CSNK1G1','ZNF609'],
        ['CSNK1G2','GANAB'],
        ['CSNK1G2','PDE5A'],
        ['CSNK2A1','SNRPB'],
        ['CTNND2','NRBP1'],
        ['CTSB','EIF2AK1'],
        ['CTSB','PXK'],
        ['CUL4B','DAPK2'],
        ['DAPK1','AGTPBP1'],
        ['DCLK1','SERPINE3'],
        ['DCLK2','UST'],
        ['DDR1','PAK1'],
        ['DDR2','FMO4'],
        ['DDX42','RPS6KB1'],
        ['DLG1','PAK2'],
        ['DNAJB1','PRKACA'],
        ['DPP4','PDK1'],
        ['DPYD','CSNK1G1'],
        ['DSTYK','NAV1'],
        ['DSTYK','NUCKS1'],
        ['DSTYK','PIGK'],
        ['DUSP22','PTK7'],
        ['DYRK1A','DSCAM'],
        ['DYRK1A','HUNK'],
        ['DYRK1A','KDM4B'],
        ['DYRK1A','TTC3'],
        ['DYRK2','CNTN2'],
        ['DYRK2','PKP1'],
        ['DYX1C1','SGK3'],
        ['E2F6','STK36'],
        ['ECHDC1','FYN'],
        ['ECT2','KALRN'],
        ['EEF2K','ACSM3'],
        ['EEF2K','C10ORF35'],
        ['EFNA3','PIK3C2G'],
        ['EGFR','SEPT14'],
        ['EHD1','ADRBK2'],
        ['EIF2AK2','CEBPZ'],
        ['EIF2AK3','PIEZO1'],
        ['EIF2AK4','ANKRD34C'],
        ['EIF2AK4','EPB42'],
        ['EIF2AK4','PKM'],
        ['EIF4ENIF1','TEX14'],
        ['ELF1','DCLK1'],
        ['ELK3','CDK17'],
        ['ELOVL6','POMK'],
        ['EML4','ALK'],
        ['EML4','CASK'],
        ['ENPP1','TESK2'],
        ['EPHA10','COL8A2'],
        ['EPHA2','HCK'],
        ['EPHA2','PREX1'],
        ['EPHA5','DGKI'],
        ['EPHA6','CNTN6'],
        ['EPHA7','PIGH'],
        ['EPHB1','BFSP2'],
        ['EPHB2','PDZD4'],
        ['EPHB3','PAX2'],
        ['EPHB3','PGC'],
        ['ERBB2','CFB'],
        ['ERBB2','CNIH4'],
        ['ERBB2','CTTN'],
        ['ERBB2','DNAJC7'],
        ['ERBB2','ENO1'],
        ['ERBB2','FKBP10'],
        ['ERBB2','GTF2E2'],
        ['ERBB2','SMIM18'],
        ['ERBB2','IFLTD1'],
        ['ERBB2','IKZF3'],
        ['ERBB2','KRT20'],
        ['ERBB2','KRT39'],
        ['ERBB2','KRTAP1-4'],
        ['ERBB2','MED1'],
        ['ERBB2','PARN'],
        ['ERBB2','PPP1R1B'],
        ['ERBB2','PSMB3'],
        ['ERBB2','SPTBN2'],
        ['ERBB2','SRCIN1'],
        ['ERBB2','TADA2A'],
        ['ERBB3','COX4I2'],
        ['ERBB4','AKAP6'],
        ['ERC1','PIK3C2G'],
        ['ERC1','RET'],
        ['ERLIN2','FGFR1'],
        ['ERN1','CASP14'],
        ['ESCO2','PTK2B'],
        ['ETV6','NTRK3'],
        ['EVC2','STK32B'],
        ['EVL','LCK'],
        ['EZR','ROS1'],
        ['FAM110A','TLK2'],
        ['FAM114A2','BRAF'],
        ['FAM20B','RALGPS2'],
        ['FAM20B','SAMD7'],
        ['FAM20C','MKRN1'],
        ['FAM49B','PSKH2'],
        ['FAM76A','ABR'],
        ['FBXL20','TLK2'],
        ['FGFR2','CASP7'],
        ['FGFR2','CCAR2'],
        ['FGFR2','CCDC6'],
        ['FGFR2','TACC2'],
        ['FGFR3','AES'],
        ['FGFR3','ELAVL3'],
        ['FGFR3','TACC3'],
        ['FHIT','CAMK4'],
        ['FIGN','STK25'],
        ['FKBP15','RET'],
        ['FLT1','OLFM4'],
        ['FLT1','SRPK2'],
        ['FN1','ERBB4'],
        ['FN1','MKNK2'],
        ['FNDC3B','PIK3CA'],
        ['FOXN1','PRKDC'],
        ['FOXN3','CDKL1'],
        ['FRK','DTNBP1'],
        ['FRMD3','BRD4'],
        ['FUNDC2','RPS6KA6'],
        ['FYN','SF1'],
        ['GAK','LUC7L3'],
        ['GAK','MAGI1'],
        ['GAK','PGC'],
        ['GFAP','DDR1'],
        ['GGA2','PRKCB'],
        ['GGA3','VRK2'],
        ['GOSR1','TAOK1'],
        ['GRHL2','NRBP2'],
        ['GRID1','BAZ1B'],
        ['GRK1','CUL4A'],
        ['GRK1','PCID2'],
        ['GRK6','DBN1'],
        ['GRK6','UIMC1'],
        ['GSK3B','ATP11B'],
        ['GSK3B','FSTL1'],
        ['GSK3B','TIAM1'],
        ['GTF2IRD1','ALK'],
        ['GXYLT2','NEK3'],
        ['HDAC7','IRAK4'],
        ['HIC2','TEC'],
        ['HIF1A','VRK1'],
        ['HIPK1','LRRC42'],
        ['HIPK2','ADCK2'],
        ['HIPK2','ARHGEF5'],
        ['HIPK2','ARPC1A'],
        ['HIPK2','DENND2A'],
        ['HIPK2','GRM8'],
        ['HIPK3','CAT'],
        ['HIPK3','GYLTL1B'],
        ['HLA-DRB1','PDK2'],
        ['HOXB6','EPHA5'],
        ['HSD17B13','CSNK1G2'],
        ['HTT','GRK4'],
        ['HUNK','MAMLD1'],
        ['HUNK','SNRPD3'],
        ['ICK','FAM83B'],
        ['IGF1R','CHD7'],
        ['IGF1R','EFTUD1'],
        ['IGF1R','GLTP'],
        ['IGF1R','PPP4R1'],
        ['IGF1R','TOLLIP'],
        ['IGF1R','TRIP4'],
        ['IGF1R','WDR93'],
        ['IGF2BP3','PRKCA'],
        ['IGF2R','ACVR2A'],
        ['IGF2R','CSF1R'],
        ['IGFBP3','LIMK1'],
        ['IKBKB','GOT1L1'],
        ['IKBKB','UNC5D'],
        ['IKBKE','ACSM1'],
        ['INPP5F','GRK5'],
        ['INSR','C7ORF72'],
        ['INSR','RBFOX3'],
        ['INSR','S1PR2'],
        ['IRAK1','PIGR'],
        ['IRAK2','SRGAP3'],
        ['IRF2BP2','NTRK1'],
        ['JAK1','ZC3H7B'],
        ['JAK2','DOCK8'],
        ['KALRN','CREB5'],
        ['KAZN','MTOR'],
        ['KAZN','TRPM7'],
        ['KCTD2','DAPK1'],
        ['KDM6A','RPS6KA3'],
        ['KDM7A','BRAF'],
        ['KIAA0430','EEF2K'],
        ['KIF5B','MET'],
        ['KIT','ANKRD11'],
#        ['KIT','PDGFRA'],
        ['KIT','SLC4A4'],
        ['KLK3','NUAK1'],
        ['KMT2C','LMTK3'],
        ['KSR1','EFCAB5'],
        ['LATS1','LACE1'],
        ['LATS1','NUP43'],
        ['LBH','FLT4'],
        ['LIMK1','TYW1'],
        ['LIPF','MELK'],
        ['LMNA','RAF1'],
        ['LMTK2','ANKIB1'],
        ['LMTK2','CA1'],
        ['LMTK2','IMMP2L'],
        ['LMTK2','RBFOX3'],
        ['LONP1','MAP2K7'],
        ['LRRFIP2','EPHA3'],
        ['LRRK1','ADAMTS17'],
        ['LRRK1','TOX4'],
        ['LRRK1','METTL3'],
        ['LRRK2','GXYLT1'],
        ['LYN','APMAP'],
        ['LYN','NTRK3'],
        ['LYN','VPS13B'],
        ['LYZ','IRAK1'],
        ['LYZ','PRKCI'],
        ['LYZ','SMG1'],
        ['LYZ','STK10'],
        ['MACF1','BRAF'],
        ['MAFF','STK16'],
        ['MAK','INTS12'],
        ['MAP2K1','CUX1'],
        ['MAP2K2','CAMKK1'],
        ['MAP2K2','INSR'],
        ['MAP2K2','PSMD9'],
        ['MAP2K3','CADM2'],
        ['MAP2K4','CD79B'],
        ['MAP2K4','DNAH9'],
        ['MAP2K4','MYH3'],
        ['MAP2K5','ADAMTSL3'],
        ['MAP2K5','RAB27A'],
        ['MAP2K7','SH3GL1'],
        ['MAP3K10','C19ORF47'],
        ['MAP3K10','SUPT5H'],
        ['MAP3K13','CCDC50'],
        ['MAP3K13','UTS2B'],
        ['MAP3K13','NSUN2'],
        ['MAP3K13','UTS2B'],
        ['MAP3K13','VKORC1'],
        ['MAP3K1','AGMO'],
        ['MAP3K1','CPLX2'],
        ['MAP3K1','PARN'],
        ['MAP3K2','SUPT3H'],
        ['MAP3K3','FCHSD2'],
        ['MAP3K5','CLVS2'],
        ['MAP3K5','NKAIN2'],
        ['MAP3K5','PERP'],
        ['MAP3K6','AHDC1'],
        ['MAP3K8','LYZL2'],
        ['MAP3K8','MROH2B'],
        ['MAP4K3','SMC6'],
        ['MAP4K4','RRBP1'],
        ['MAP4K4','SYF2'],
        ['MAP4K5','JAM3'],
        ['MAP4K5','NIN'],
        ['MAP4K5','THSD7A'],
        ['MAP4K5','TRIM9'],
        ['MAPK14','MICU2'],
        ['MAPK14','SIN3A'],
        ['MAPK1','FAM155A'],
        ['MAPK1','KCNJ4'],
        ['MAPK1','PRODH'],
        ['MAPK1','SSU72'],
        ['MAPK8','RAP1B'],
        ['MAPK9','DGKB'],
        ['MAPKAPK2','CDC42BPG'],
        ['MAPKAPK2','IQSEC3'],
        ['MAPKAPK2','PLA2G2A'],
        ['MAPKAPK5','GNPTAB'],
        ['MARK1','RHOU'],
        ['MARK2','BATF2'],
        ['MARK2','BUB1B'],
        ['MARK2','C11ORF84'],
        ['MARK2','FAM168A'],
        ['MARK2','RTN3'],
        ['MARK3','EIF5'],
        ['MARK3','FBLN5'],
        ['MARK3','KIF26A'],
        ['MARK3','MIA2'],
        ['MARK3','PDIA4'],
        ['MARK3','SLC25A21'],
        ['MARK4','LYPD5'],
        ['MAST2','C6ORF52'],
        ['MAST2','COQ6'],
        ['MAST2','MMEL1'],
        ['MAST2','PSMA5'],
        ['MAST4','LRP1B'],
        ['MAST4','NLN'],
        ['MAST4','PLIN2'],
        ['MAST4','SREK1IP1'],
        ['MASTL','SEL1L'],
        ['MBOAT2','CSNK1G1'],
        ['MDGA2','SRPK2'],
        ['MDM2','SYK'],
        ['MED21','PIP5K1C'],
        ['MED25','MAPK15'],
        ['MELK','CCDC117'],
        ['MELK','SDK1'],
        ['METTL5','TLK1'],
        ['METTL7A','SRPK1'],
        ['MFGE8','IGF1R'],
        ['MGA','EPHA5'],
        ['MIEN1','CDK12'],
        ['MINK1','ALOX12'],
        ['MINK1','NQO2'],
        ['MINK1','SPNS3'],
        ['MKLN1','CDK14'],
        ['MKRN1','BRAF'],
        ['MLKL','TMEM231'],
        ['MOB3A','STK11'],
        ['MOK','ANKRD66'],
        ['MOK','MUCL1'],
        ['MOK','WARS'],
        ['MOV10','STK25'],
        ['MPRIP','RAF1'],
        ['MRAS','NME9'],
        ['MRPS6','MYO3A'],
        ['SLC5A3','MYO3A'],
        ['MST1R','FNDC3B'],
        ['MTF2','BRDT'],
        ['MTSS1','ERBB2'],
        ['MYLK','NXPH1'],
        ['MYLK','TM7SF2'],
        ['MYO3B','IL1RAPL2'],
        ['MYO3B','TSHZ2'],
        ['NAP1L1','STK38L'],
        ['NARS2','PAK1'],
        ['NAT8','PDK4'],
        ['NBPF3','EPHB2'],
        ['NCOA3','SGK2'],
        ['NCOA4','RET'],
        ['NDE1','EPHA7'],
        ['MYH11','EPHA7'],
        ['NDE1','TRIO'],
        ['MYH11','TRIO'],
        ['NDE1','WNK2'],
        ['MYH11','WNK2'],
        ['NDUFA7','PRKCG'],
        ['NEK11','BDH1'],
        ['NEK1','GALNTL6'],
        ['NEK4','SETD2'],
        ['NEK6','PSMB7'],
        ['NEK6','PTGS1'],
        ['NEK7','CD1C'],
        ['NEK7','CRB1'],
        ['NEK7','RAB3GAP2'],
        ['NEK8','FAM222B'],
        ['NEK9','TMED10'],
        ['NF1','TEX14'],
        ['NFASC','NTRK1'],
        ['NFIB','PIM2'],
        ['NIPBL','STK24'],
        ['NLK','BCAS3'],
        ['NLK','ELMO1'],
        ['NLK','LGALS9'],
        ['NLK','NF1'],
        ['NLK','RAD51D'],
        ['NME4','TMC5'],
        ['NRBP1','DROSHA'],
        ['NRBP1','RAB10'],
        ['NUAK1','C12ORF65'],
        ['NUAK1','UHRF1BP1L'],
        ['NUAK2','CYB5R1'],
        ['NUAK2','LEMD1'],
        ['NUAK2','RBM24'],
        ['NUMB','TAOK3'],
        ['NUP210L','EEF2K'],
        ['NVL','NEK2'],
        ['OBSCN','CASZ1'],
        ['OBSCN','DISC1'],
        ['OBSCN','IGSF21'],
        ['OSBPL2','ADCK1'],
        ['OXR1','MET'],
        ['OXSR1','ATXN7'],
        ['P4HA1','CAMK2G'],
        ['PA2G4','MARK1'],
        ['PAK1','CNIH4'],
        ['PAK1','KCTD21'],
        ['PAK1','LNP1'],
        ['PAK1','MYO7A'],
        ['PAK1','NARS2'],
        ['PAK1','PDGFD'],
        ['PAK2','BDH1'],
        ['PAK2','DLG1'],
        ['PAK2','ECE2'],
        ['PAK4','CACNG6'],
        ['PAK4','CYP2A6'],
        ['PAK4','L3MBTL4'],
        ['PAK4','LSM4'],
        ['PAN3','FLT3'],
        ['PAN3','NTRK2'],
        ['PANK2','PAK7'],
        ['PAPD7','RAF1'],
        ['PARP14','TTBK1'],
        ['PASK','BOK'],
        ['PAWR','BMPR1B'],
        ['PDGFRA','FIP1L1'],
        ['PDGFRA','LNX1'],
        ['PDGFRB','FBLN1'],
        ['PDK3','NAV3'],
        ['PDK4','CALD1'],
        ['PDK4','ENO1'],
        ['PDK4','GRID2'],
        ['PDPK1','CCNF'],
        ['PDPK1','MAPK8IP3'],
        ['PEAK1','ANGPT1'],
        ['PEAK1','CIB2'],
        ['PEAK1','COL1A1'],
        ['PEAK1','NRG4'],
        ['PEAK1','PSTPIP1'],
        ['PEAK1','TM9SF3'],
        ['PEAK1','VPS33B'],
        ['PGC','AKT1'],
        ['PGC','CSNK1D'],
        ['PGC','EPHB3'],
        ['PGC','EPHB4'],
        ['PHACTR4','PIP5K1A'],
        ['PI4K2A','C10ORF32'],
        ['PI4K2A','AS3MT'],
        ['PI4K2A','ZDHHC16'],
        ['PI4K2B','C2ORF61'],
        ['PI4KA','CDH10'],
        ['PI4KA','LZTR1'],
        ['PI4KA','MYO18B'],
        ['PI4KA','PHF21B'],
        ['PI4KB','SELENBP1'],
        ['PIK3C3','TRPC6'],
        ['PIK3CB','BFSP2'],
        ['PIK3CB','KCNAB1'],
        ['PIK3CB','PCCB'],
        ['PIK3CB','TSPO'],
        ['PIKFYVE','MLPH'],
        ['PIKFYVE','TDRD3'],
        ['PIKFYVE','ZNF124'],
        ['PIM1','AFF1'],
        ['PIP4K2A','ARHGAP21'],
        ['PIP4K2B','CWC25'],
        ['PIP4K2B','MED24'],
        ['PIP4K2B','MLLT6'],
        ['PIP5K1A','ITLN1'],
        ['PIP5K1A','MLLT11'],
        ['PIP5K1A','CDC42SE1'],
        ['PIP5K1B','PGM5'],
        ['PIP5K1C','MATK'],
        ['PIP5K1C','PALM'],
        ['PIP5K1C','PPM1H'],
        ['PKMYT1','CLDN6'],
        ['PKN3','CYTH3'],
        ['PKN3','TRIM65'],
        ['PLCB1','ROR1'],
        ['PLS1','PIK3CB'],
        ['PMEL','NRBP1'],
        ['PMEL','RIPK4'],
        ['POFUT1','HCK'],
        ['POLA1','MAP3K15'],
        ['POMK','CHRNA6'],
        ['POMK','LSS'],
        ['POMK','NKAIN3'],
        ['POMK','ST6GAL1'],
        ['POU2F1','EPHA4'],
        ['PPFIA1','MARK2'],
        ['PPM1A','ADCK4'],
        ['PPP6R1','AURKC'],
        ['PRKAA1','TBC1D5'],
        ['PRKAA2','USP24'],
        ['PRKCD','FANCD2OS'],
        ['PRKCD','FANCD2'],
        ['PRKCE','GPR126'],
        ['PRKCE','TRIM13'],
        ['PRKCI','GPR160'],
        ['PRKCI','PTBP2'],
        ['PRKCZ','PRDM16'],
        ['PRKD2','CKM'],
        ['PRKD2','HPSE2'],
        ['PRKD2','MYH14'],
        ['PRKD3','TMEM51'],
        ['PRKDC','ATF5'],
        ['PRKDC','CEP290'],
        ['PRKDC','CSMD1'],
        ['PRKDC','DEFB103B'],
        ['PRKDC','GSR'],
        ['PRKDC','PXDNL'],
        ['PRKDC','SPIDR'],
        ['PRKG1','ANXA1'],
        ['PRKG1','TRIM5'],
        ['PRKG1','TRIM22'],
        ['PRPF4B','F13A1'],
        ['PSEN1','STK4'],
        ['PSPH','PHKG1'],
        ['PTAR1','PIP5K1B'],
        ['PTK2','AGO2'],
        ['PTK2','ANGPT1'],
        ['PTK2','ANKRD11'],
        ['PTK2','CACNG8'],
        ['PTK2','CHKA'],
        ['PTK2','DENND3'],
        ['PTK2','MKLN1'],
        ['PTK2','PPP2R5E'],
        ['PTK2','RNF139'],
        ['PTK7','CNOT2'],
        ['PTK7','DLK2'],
        ['PTPRD','RPS6KC1'],
        ['PTPRZ1','MET'],
        ['PXK','FLNB'],
        ['PXK','RPP14'],
        ['R3HDM2','PIP4K2C'],
        ['RAB3B','PKN2'],
        ['RAB3GAP2','NEK7'],
        ['RAB8A','MAP2K2'],
        ['RAF1','AGGF1'],
        ['RAI14','MAPK9'],
        ['RAP1B','SCYL2'],
        ['RASSF3','TBK1'],
        ['RBM19','CLK2'],
        ['RBPMS','NTRK3'],
        ['RFWD3','STK31'],
        ['RHOT1','FGFR1'],
        ['RIMKLB','PIP4K2A'],
        ['RIOK1','AKR1D1'],
        ['RIOK1','USP45'],
        ['RIOK3','TAF4B'],
        ['RIPK1','BCKDHB'],
        ['RNF170','YES1'],
        ['RNF40','PLK1'],
        ['ROCK1','ABHD3'],
        ['ROCK1','ANKRD29'],
        ['ROCK1','DCC'],
        ['ROCK1','GATA6'],
        ['ROCK1','LAMA3'],
        ['ROCK1','LRIG3'],
        ['ROCK1','RBM47'],
        ['ROCK1','RNF38'],
        ['ROCK2','BLM'],
        ['ROCK2','MEIS1'],
        ['ROCK2','NTSR2'],
        ['ROCK2','PPP2CA'],
        ['ROR1','CA10'],
        ['ROR1','DNAJC6'],
        ['RPA1','GUCY2D'],
        ['RPL19','PAK2'],
        ['RPN2','STK17A'],
        ['RPS6KA1','RASGRP3'],
        ['RPS6KA2','IGF2BP3'],
        ['RPS6KA2','KIFC1'],
        ['RPS6KA2','MCHR2'],
        ['RPS6KA3','BMX'],
        ['RPS6KA3','FAM156B'],
        ['RPS6KA3','KDM6A'],
        ['RPS6KA6','HDX'],
        ['RPS6KB1','EFCAB3'],
        ['RPS6KB1','RNF213'],
        ['RPS6KB2','C10ORF54'],
        ['RPS6KB2','PPP1CA'],
        ['RPS6KB2','ST3GAL2'],
        ['RPS6KC1','LYST'],
        ['RPS6KC1','TFPI'],
        ['RRM2B','STK3'],
        ['RYK','ITFG1'],
        ['RYK','RABL3'],
        ['SCYL1','FRMD8'],
        ['SCYL1','PACS1'],
        ['SCYL2','ANKS1B'],
        ['SCYL2','FAM71C'],
        ['SCYL2','C12ORF79'],
        ['SCYL2','GIT2'],
        ['SCYL3','KIFAP3'],
        ['SCYL3','PDZRN4'],
        ['SDHA','PDGFRB'],
        ['SGK1','NRROS'],
        ['SGK1','PDSS2'],
        ['SGK1','PGC'],
        ['SHB','LYN'],
        ['SIK2','CARD17'],
        ['SIK2','MEGF11'],
        ['SIK2','PIR'],
        ['SIK2','RBFOX1'],
        ['SIK3','CD3D'],
        ['SIK3','UBR1'],
        ['SLC34A2','ROS1'],
        ['SLC39A6','MAST2'],
        ['SMAD3','MAP2K1'],
        ['SMEK2','ALK'],
        ['SMG1','NDE1'],
        ['SMG1','MYH11'],
        ['SMS','DYRK2'],
        ['SND1','BRAF'],
        ['SNRNP40','MAP2K5'],
        ['SNTG2','TRPM6'],
        ['SP3','STK39'],
        ['SPAG16','YES1'],
        ['SPECC1L','RET'],
        ['SPINT2','PAK1'],
        ['SPNS1','PRKCB'],
        ['SPRN','ADCK3'],
        ['CYP2E1','ADCK3'],
        ['SQSTM1','NTRK1'],
        ['SQSTM1','NTRK2'],
        ['SRC','GSS'],
        ['SRC','MANBAL'],
        ['SRI','PIP4K2C'],
        ['SRPK1','ANKRD42'],
        ['SRPK1','CEP57L1'],
        ['SRPK1','DDAH1'],
        ['SRPK1','EHMT2'],
        ['SRPK2','KIAA1324L'],
        ['SRPK2','LRP5'],
        ['SRPK2','PUS7'],
        ['SSBP2','NTRK1'],
        ['STAG2','EPHB1'],
        ['STAG2','PAK3'],
        ['STARD3','STRADA'],
        ['STK10','GNS'],
        ['STK10','HN1L'],
        ['STK10','SH3PXD2B'],
        ['STK10','SNX2'],
        ['STK10','UBE2D2'],
        ['STK11','BSG'],
        ['STK11','HMHA1'],
        ['STK11','KDM4B'],
        ['STK11','SMARCD2'],
        ['STK11','TYK2'],
        ['STK16','PLCD4'],
        ['STK19','LY6G6D'],
        ['STK24','ANKS1B'],
        ['STK24','ATF7'],
        ['STK24','PIP5K1B'],
        ['STK24','SLC35F1'],
        ['STK24','TMTC4'],
        ['STK24','TRIQK'],
        ['STK32A','SPINK5'],
        ['STK32B','SMIM14'],
        ['STK35','CHD6'],
        ['STK38','ANKRD28'],
        ['STK38L','CCDC91'],
        ['STK38','TDRD7'],
        ['STK38','ZNF184'],
        ['STK39','MAT1A'],
        ['STK39','NCKAP5'],
        ['STK39','TMEM245'],
        ['STK3','MRPL48'],
        ['STK3','PCLO'],
        ['STK3','POLR2K'],
        ['STK3','SPRR2E'],
        ['STK3','SPRR2B'],
        ['STK3','SULT1A3'],
        ['STK3','ZNF706'],
        ['STK40','MDM4'],
        ['STK40','RBBP4'],
        ['STK4','C20ORF197'],
        ['STK4','FOXP1'],
        ['STK4','PKIG'],
        ['STK4','TSHZ2'],
        ['STRADA','LYZ'],
        ['STRN','ALK'],
        ['SUDS3','CDK4'],
        ['SYNJ2','CDK19'],
        ['TANC2','PRKCA'],
        ['TANC2','STRADA'],
        ['TAOK1','ABHD15'],
        ['TAOK1','ACER3'],
        ['TAOK1','ASGR2'],
        ['TAOK1','BCAS3'],
        ['TAOK1','C17ORF105'],
        ['TAOK1','CPD'],
        ['TAOK1','NLK'],
        ['TAOK1','PARD6G'],
        ['TAOK1','VMP1'],
        ['TAOK1','ZNF207'],
        ['TAOK2','GPR56'],
        ['TAOK3','RNF11'],
        ['TAX1BP1','BRAF'],
        ['TBC1D9','PLK4'],
        ['TBCK','SLC9B2'],
        ['TBK1','GRIP1'],
        ['TBL1XR1','MAST3'],
        ['TBL1XR1','PIK3CA'],
        ['TBL1XR1','RET'],
        ['TBL1XR1','ROCK1'],
        ['TDRD3','PIKFYVE'],
        ['TEAD4','MAP3K12'],
        ['TEC','HMGCLL1'],
        ['TEC','NCAM2'],
        ['TEC','PASD1'],
        ['TECR','PKN1'],
        ['TESK2','GPR37L1'],
        ['TEX14','CLTC'],
        ['TEX14','MSI2'],
        ['TEX261','AAK1'],
        ['TFG','MET'],
        ['TFG','NTRK1'],
        ['TGFBR1','COL15A1'],
        ['TGFBR2','XPC'],
        ['TG','GAK'],
        ['TG','MINK1'],
        ['SLA','MINK1'],
        ['TG','WNK3'],
        ['THSD4','DSTYK'],
        ['TIAM1','MAP3K2'],
        ['TIMP3','SCYL3'],
        ['SYN3','SCYL3'],
        ['TJP1','PEAK1'],
        ['TLK1','CAT'],
        ['TLK1','CREG2'],
        ['TLK2','IRAK3'],
        ['TLK2','KCNJ16'],
        ['TLK2','PITPNC1'],
        ['TLK2','SIGLEC9'],
        ['TMC1','ADCK1'],
        ['TMEM127','ZAP70'],
        ['TMEM159','STK24'],
        ['TMEM165','PDGFRA'],
        ['TMEM241','RIOK3'],
        ['TMEM39A','EPHA6'],
        ['TMEM87B','MERTK'],
        ['TNIK','CLIP1'],
        ['TNIP1','CAMK2A'],
        ['TOP2A','TTBK2'],
        ['TOPBP1','NEK11'],
        ['TP53RK','ZNF227'],
        ['TPM1','ALK'],
        ['TPM3','NTRK1'],
        ['TRABD','DDR2'],
        ['TRAK1','RAF1'],
        ['TRAPPC10','SIK1'],
        ['TRIB1','SLC25A32'],
        ['TRIM24','BRAF'],
        ['TRIM24','NTRK2'],
        ['TRIM27','RET'],
        ['TRIM33','RET'],
        ['TRIM52','DAPK1'],
        ['TRIO','ADAMTS12'],
        ['TRIO','ASTN1'],
        ['TRIO','CDH4'],
        ['TRIO','CLIC5'],
        ['TRIO','CLNK'],
        ['TRIO','DNAH5'],
        ['TRIO','FBXL7'],
        ['TRIO','IFT52'],
        ['TRIO','LIFR'],
        ['TRIO','SLC9A3'],
        ['TRIO','TERT'],
        ['TRRAP','ANKIB1'],
        ['TRRAP','TMEM168'],
        ['TTBK2','TOP2A'],
        ['TTC13','JAK2'],
        ['TTK','TMEM63B'],
        ['TUBD1','RPS6KB1'],
        ['TUFT1','PKN2'],
        ['TXLNA','SBK1'],
        ['TYK2','FGD3'],
        ['TYK2','SHC2'],
        ['TYRO3','TTR'],
        ['UACA','LTK'],
        ['UBE2H','NEK11'],
        ['UHMK1','DCAF8'],
        ['UHMK1','FBXL7'],
        ['UHMK1','PPOX'],
        ['ULK1','FBXW8'],
        ['ULK1','SFSWAP'],
        ['ULK2','DOCK6'],
        ['ULK2','UQCR11'],
        ['ULK2','MBD3'],
        ['USP32','EPHA1'],
        ['USP8','TRPM7'],
        ['UTRN','SGK1'],
        ['UVRAG','CDK8'],
        ['VEGFA','STK38'],
        ['VPREB1','RPS6KA3'],
        ['VRK3','PARP4'],
        ['VRK3','POU2F2'],
        ['VRK3','PTOV1'],
        ['VRK3','SEMA3C'],
        ['VTI1A','PIK3CB'],
        ['WASF2','FGR'],
        ['WEE2','APOBEC3B'],
        ['WHSC1L1','FGFR1'],
        ['WNK1','B4GALNT3'],
        ['WNK1','FAM155A'],
        ['WNK1','GIPC1'],
        ['WNK1','IQSEC3'],
        ['WNK1','KDM5A'],
        ['WNK1','MANBA'],
        ['WNK1','PGC'],
        ['WNK1','PRMT8'],
        ['WNK1','RAD52'],
        ['WNK1','STK38L'],
        ['WNK1','WNT5B'],
        ['WNK2','IGF2'],
        ['WRB','NLK'],
        ['WWTR1','ATR'],
        ['XRN1','PIP4K2A'],
        ['YES1','COL26A1'],
        ['YES1','SCFD2'],
        ['ZC3HAV1','BRAF'],
        ['ZNF114','PRKDC'],
        ['ZNF253','BAZ1A'],
        ['ZNF292','MAP3K4'],
        ['ZNF37A','PIP5K1B'],
        ['ZNF436','FLT1'],
        ['ZNF577','FGFR1'],
        ['ZNF587','BRSK1'],
        ['ZNF791','FGFR1'],
        ['ACSS1','APMAP'],
        ['ADAP2','RNF135'],
        ['C1ORF196','KAZN'],
        ['CCNH','C5ORF30'],
#        ['FZD4','RP11-736K20.5'],
        ['IGLV2-8','IGLL5'],
        ['KDM4A','AC011523.2'],
        ['KDM4B','AC011523.2'],
#        ['LRRC59','FLJ60017'],
        ['MAN2A1','FER'],
#        ['MTIF2','AL592494.3'],
        ['MTOR','TP53BP1'],
        ['NAP1L1','CCDC88C'],
        ['RIPK1','SERPINB9'],
        ['RP11-168J18.6','PPP2R5C'],
        ['RP11-356O9.1','TTC6'],
        ['RP11-381K20.2','KLHL3'],
        ['RP11-386M24.4','H2AFV'],
#        ['RP11-443D10.3','ACACB'],
#        ['RP11-550F7.1','CAP1'],
        ['RPL38','AC007283.4'],
        ['SLC45A2','AMACR'],
        ['TLK2','RP11-274B21.1'],
        ['TMC5','CCP110'],
        ['TMEM135','CCDC67'],
        ['TMEM137','CCDC67'],
        ['TMPRSS2','ERG'],
        ['TRMT11','GRIK2'],
        ['UBA52','CTA-242H14.1'],
#        ['ZNF720','RP11-488L18.4'],
        ['BRD4','NUT'],
        ['BRD3','NUT'],
        ['NSD3','NUT'],
        ['SETD1B','GTF2H3'],
        ['HIP1','ALK'],
        ['ZC3H7B','BCOR'],
        ['MEAF6','PHF1'],
        ['EPC1','PHF1'],
        ['KLC1','ALK'],
        ['TPR','ALK'],
        ['TTC40','MSI2'],
        ['MPP5','FAM71D'],
        ['ARHGEF3','C8ORF38'],
        ['AC010724.1','CPEB1'],
        ['ADAMTS2','RP11-798K23.4'],
        ['ANTXR1','GKN1'],
        ['ASAP1','ADCY8'],
        ['ATXN7','FHIT'],
        ['B4GALT2','ZSWIM5'],
        ['C9ORF3','PRUNE2'],
        ['CPSF3','ASAP2'],
        ['CTNNB1','PLAG1'],
        ['DCUN1D1','MCCC1'],
        ['DNAH11','RAPGEF5'],
        ['DPP6','ACTR3B'],
        ['EEF2','ENHO'],
        ['EPC2','MORC1'],
        ['EPC2','MORC1-AS1'],
        ['ERBB2','LTBP4'],
#        ['MMACHC','RP11-435B5.7'],
        ['NONO','TFE3'],
        ['PARG','BMS1'],
        ['PHF3','PTP4A1'],
        ['PLOD2','CCNYL1'],
        ['POLR2G','CYP1A2'],
        ['PTER','MSRB2'],
        ['RAGE','EML1'],
        ['RBM10','TFE3'],
        ['RIC8A','RP11-34P13.7'],
        ['NUTM2A-AS1','MINPP1'],
        ['RP1-45C12.1','KIFAP3'],
        ['SEMA6A','CAMK4'],
        ['TEX264','FAM107A'],
        ['TFE3','RBM10'],
        ['TMED6','COG8'],
        ['TPPP','TERT'],
        ['UPF3A','CDC16'],
        ['PVT1','NSMCE2'],
        ['CCDC26','NSMCE2'],
        ['ABL1','ANXA4'],
        ['ACTG1','PDLIM5'],
        ['ADARB1','PCBP3'],
        ['ANXA4','TMEM67'],
        ['BMPR1B','PDLIM5'],
        ['BPTF','METTL2A'],
        ['C15ORF21','MYC'],
        ['C2CD3','SMAD9'],
        ['CAPN7','FGD5'],
        ['CCDC112','CDC25C'],
        ['CCDC50','DSCAM'],
        ['CCND3','FGF11'],
        ['CCNT1','HECTD4'],
        ['CHN1','ACVR1C'],
        ['CNTNAP2','C2ORF3'],
        ['CPNE4','ACAD11'],
        ['CREB1','CCNYL1'],
        ['DCP2','UBR1'],
        ['DENND1A','ANXA4'],
        ['DHODH','NDUFAB1'],
        ['DTNB','CLASP1'],
        ['DTNB','SPTLC1'],
        ['EIF4E3','IQSEC1'],
        ['EIF4G3','SESN2'],
        ['FH','RP5-827C21.6'],
        ['FLT4','RRP7A'],
        ['FOXA1','ETV1'],
        ['FUBP1','ETV1'],
        ['FZD6','SDC2'],
        ['GNL2','EIF4G3'],
        ['GPR107','C2ORF28'],
        ['GRIN2B','TMEM87A'],
        ['HDAC5','GPATCH8'],
        ['HECTD4','PSD3'],
        ['INHBB','CLASP1'],
        ['KIAA2013','CNTNAP2'],
        ['KIAA2026','UHRF2'],
        ['LAMC1','PIK3C2B'],
        ['LARP4B','PPIL4'],
        ['LCOR','RP11-452K12.4'],
        ['MAP3K5','TCF12'],
        ['MAP4K3','CWC22'],
        ['MATR3','HMGB3P22'],
        ['METAP2','PIK3C2G'],
        ['MPND','RAB8A'],
        ['N4BP1','VPS35'],
        ['NARS2','TMPRSS2'],
        ['NDRG1','ERG'],
        ['NFATC3','EIF4G2'],
        ['NUP153','NTNG2'],
        ['ODZ1','ENOX2'],
        ['PDS5A','KLB'],
        ['PDZRN3','MAGI1'],
        ['PHF17','ZFHX3'],
        ['PPIL4','SEC63'],
        ['PRKDC','RP11-770E5.1'],
        ['PSEN1','GJB1'],
        ['RALGPS1','EXOC6B'],
        ['SEC63','LARP4B'],
        ['SETX','PRRC2A'],
        ['SHANK2','ARHGEF17'],
        ['SLC35D2','LPPR1'],
        ['SLC45A3','FAM48A'],
        ['SLIT1','ATAD1'],
        ['SMAD4','MICALCL'],
        ['SORT1','CXORF21'],
        ['STK39','PAX3'],
        ['TANC1','ITGB6'],
        ['TCF12','AQP9'],
        ['TCF12','GRIN2B'],
        ['TENC1','TP53'],
        ['TJP2','GRIN3A'],
        ['TMEM55A','LCLAT1'],
        ['TMEM87A','TCF12'],
        ['TMPRSS2','ERG'],
        ['TMPRSS2','ZFAT'],
        ['TMTC4','SH3KBP1'],
        ['TP53','ALOXE3'],
        ['TP53','SHBG'],
        ['TSC22D1','RB1'],
        ['UBE2E1','RARB'],
        ['UBR2','CCND3'],
        ['USP32','MARCH10'],
        ['VPRBP','CCDC50'],
        ['WDTC1','EFCAB4A'],
        ['ZFAT','CRLS1'],
        ['ZNF618','MUSK'],
        ['ZNF638','KCNS3'],
        ['SND1','BRAF'],
        ['BRAF','HERPUD1'],
        ['BRAF','ZSCAN30'],
        ['BRAF','GATM'],
        ['HACL1','RAF1'],
        ['GTF2I','RARA'],
        ['PTPRZ','MET'],
        ['RNF213','SLC26A11'],
        ['AHCYL2','TMEM178B'],
        ['AP2A2','SBF2'],
        ['APEH','SHISA5'],
        ['B4GALNT3','DENND5B'],
        ['BCR','LZTR1'],
        ['BIN2','CELA1'],
        ['BRPF3','CLPSL1'],
#        ['C15ORF57','CBX3'],
        ['CBL','FBXO2'],
        ['CCM2','OGDH'],
        ['CD81','SPAG6'],
        ['CDK17','KCNC2'],
        ['CDK4','TSFM'],
        ['CLASRP','SYMPK'],
        ['COG3','GPC6'],
        ['CPNE5','ANXA6'],
        ['CTDSP2','XRCC6BP1'],
        ['FAM155A','COL4A1'],
        ['FARP2','DTNB'],
        ['FGFR3','TACC3'],
        ['FRMD4A','PFKP'],
        ['GLTP','VPS29'],
        ['GPR162','CCDC39'],
        ['HUWE1','RIBC1'],
        ['IFT80','MLH1'],
        ['IL1RAP','FGF12'],
        ['LANCL2','DNAH11'],
        ['LHFP','SERP2'],
        ['MARCH6','MYO10'],
        ['MED13L','GRIP1'],
        ['MGAT5','KIAA0825'],
        ['MLL3','CHGB'],
        ['MRPS28','ASPH'],
        ['MTAP','C9ORF92'],
        ['NEK6','RXRA'],
        ['NFATC3','CPNE2'],
        ['PITPNA','RAD51C'],
        ['PLA2G6','CRYBB1'],
        ['PLAGL2','HCK'],
        ['PODXL','BGN'],
        ['PTN','DGKI'],
        ['PTPRZ1','MET'],
        ['PVRL2','SNTG1'],
        ['RASSF7','SCUBE2'],
        ['RNF213','SLC26A11'],
        ['SH3GL1','CHAF1A'],
        ['SLC6A8','GABRA3'],
        ['ST7','CTTNBP2'],
        ['TCF7L1','KIF1B'],
        ['TGFB1','SAE1'],
        ['TPM3','ADAR'],
        ['TPT1','AADAT'],
        ['TTLL11','FIBCD1'],
        ['URI1','SLC6A20'],
        ['VEZT','CORO1C'],
        ['VHL','BRK1'],
        ['ZC3H11A','REN'],
        ['ZMIZ1','MAT1A'],
        ['ZNF197','CHMP2B'],
        ['A2M','NOL10'],
        ['ACER3','PAK1'],
        ['ADNP2','ITGB3BP'],
        ['AGAP2','TSFM'],
        ['AHCYL2','TMEM178B'],
        ['ANO4','GALNT9'],
        ['AP2A2','SBF2'],
        ['APEH','SHISA5'],
        ['AVIL','VSNL1'],
        ['B4GALNT3','DENND5B'],
        ['BAZ2A','LRP1'],
        ['BAZ2A','METTL1'],
        ['BCAT1','FIP1L1'],
        ['BCR','LZTR1'],
        ['BIN2','CELA1'],
        ['BRPF3','CLPSL1'],
        ['C12ORF5','KCNC2'],
        ['C15ORF57','CBX3'],
        ['C1ORF21','MIXL1'],
        ['C2CD3','SMAD9'],
        ['C2ORF48','PRMT8'],
        ['CBL','FBXO2'],
        ['CCDC136','FKBP9L'],
        ['CCM2','OGDH'],
        ['CD81','SPAG6'],
        ['CDK17','KCNC2'],
        ['CDK4','TSFM'],
        ['CHFR','SMARCD1'],
        ['CHST3','PTCH2'],
        ['CLASRP','SYMPK'],
        ['CLSTN1','KAZN'],
        ['COG3','GPC6'],
        ['COL22A1','BMP7'],
        ['COL4A2','FAM155A'],
        ['COQ10A','NINJ2'],
        ['CPNE5','ANXA6'],
        ['CS','STAT6'],
        ['CTC1','TMEM117'],
        ['CTDSP2','SLC6A15'],
        ['CTDSP2','XRCC6BP1'],
        ['CTNND1','TMEM135'],
        ['CUL1','CNTNAP2'],
        ['CXADR','C21ORF37'],
        ['DENND4C','ADAMTSL1'],
        ['DEPDC5','ALDH18A1'],
        ['DGKE','CACNA1G'],
        ['DHX35','LPAR1'],
        ['DNAJC3','RNASEH2B-AS1'],
        ['EDC3','COX5A'],
        ['EGFR','VSTM2A'],
        ['ELAVL2','PLGRKT'],
        ['ELK1','GPRC5A'],
        ['EML1','EVL'],
        ['ESAM','MSANTD2'],
        ['ETV6','NELL2'],
        ['FAM117A','LGALS9'],
        ['FAM155A','COL4A1'],
        ['FAM222A','MVK'],
        ['FAM222A','SIRT4'],
        ['FARP2','DTNB'],
        ['FGFR3','TACC3'],
        ['FOXP2','CAPZA2'],
        ['FOXP2','MET'],
        ['FRMD4A','PFKP'],
        ['GLTP','VPS29'],
        ['GOLPH3','APBB1IP'],
        ['GPR162','CCDC39'],
        ['GRIP1','RNFT2'],
        ['GRIP1','SOX5'],
        ['HUWE1','RIBC1'],
        ['IFT80','MLH1'],
        ['IFT81','ETNK1'],
        ['IL1RAP','FGF12'],
        ['IP6K2','USP19'],
        ['IQSEC1','GP1BA'],
        ['JAK1','HIVEP3'],
        ['KIAA0430','SPR'],
        ['KSR1','PKN3'],
        ['LAMA1','PTPRM'],
        ['LANCL2','DNAH11'],
        ['LHFP','SERP2'],
        ['LINC00662','AP1M2'],
        ['LMBR1L','GALNT9'],
        ['LNX2','LHFP'],
        ['LPCAT1','DENND3'],
        ['LRP1','BAZ2A'],
        ['LRRFIP2','GOLGA4'],
        ['MACF1','AHDC1'],
        ['MARCH6','MYO10'],
        ['MARCH9','SLCO1B7'],
        ['MAX','TTC7B'],
        ['MECOM','GAP43'],
        ['MED13L','GRIP1'],
        ['MED13L','YEATS4'],
        ['MGAT5','KIAA0825'],
        ['MID1','ARHGAP6'],
        ['MLL3','CHGB'],
        ['MRPS28','ASPH'],
        ['MSANTD2','ESAM'],
        ['MTAP','C9ORF92'],
        ['MYO6','SENP6'],
        ['NAB2','TAC3'],
        ['NEK6','RXRA'],
        ['NFATC3','CPNE2'],
        ['NMU','LNX1'],
        ['NPAT','RPS11'],
        ['NUS1','SLC25A13'],
        ['PAK4','AKT2'],
        ['PAK4','NFKBIB'],
        ['PER3','CAMTA1'],
        ['PITPNA','RAD51C'],
        ['PITPNM2','ACSS3'],
        ['PLA2G6','CRYBB1'],
        ['PLAGL2','HCK'],
        ['PLGRKT','HSPBP1'],
        ['PODXL','BGN'],
        ['POLN','SH3BP2'],
        ['PPP1R12A','C12ORF42'],
        ['PPP1R12A','OS9'],
        ['PPP6R1','MLLT3'],
        ['PRMT8','LAPTM4A'],
        ['PTEN','COL17A1'],
        ['PTN','DGKI'],
        ['PTPN1','CHMP4B'],
        ['PTPRZ1','MET'],
        ['PVRL2','SNTG1'],
        ['PXDC1','NFS1'],
        ['RAB3C','CNTN5'],
        ['RASSF7','SCUBE2'],
        ['RBMS2','LRP1'],
        ['RDH16','R3HDM2'],
        ['RIMKLB','MICALL2'],
        ['RNF213','SLC26A11'],
        ['RNFT2','MYO1A'],
        ['RPAP3','CPNE8'],
        ['RRN3P2','ANK2'],
        ['RTN3','TRPC6'],
        ['SCHIP1','ACOT9'],
        ['SCMH1','LIMA1'],
        ['SCUBE2','ZNF195'],
        ['SEC61G','LANCL2'],
        ['SFMBT1','CCRL2'],
        ['SFSWAP','TCP11L2'],
        ['SH3GL1','CHAF1A'],
        ['SIGLEC8','MBOAT7'],
        ['SLC2A8','KPNA3'],
        ['SLC6A8','GABRA3'],
        ['SMARCC2','TSFM'],
        ['SORL1','CNTNAP2'],
        ['SP1','TMEM132D'],
        ['SREBF2','EFCAB6'],
        ['SRGAP3','TATDN2'],
        ['SSH2','RTN1'],
        ['SSPN','GRIN2B'],
        ['ST7','CTTNBP2'],
        ['STAT2','CD9'],
        ['STAU1','CABP5'],
        ['STK3','VPS13B'],
        ['TCF7L1','KIF1B'],
        ['TFDP2','LMBRD1'],
        ['TFRC','IL1RAP'],
        ['TGFB1','SAE1'],
        ['TMEM117','CTC1'],
        ['TOM1L2','IGSF9B'],
        ['TPM3','ADAR'],
        ['TPT1','AADAT'],
        ['TRMT6','C11ORF34'],
        ['TSFM','R3HDM2'],
        ['TTC19','ADORA2B'],
        ['TTLL11','FIBCD1'],
        ['UBE3C','CNTNAP2'],
        ['URI1','SLC6A20'],
        ['VEZT','CORO1C'],
        ['VHL','BRK1'],
        ['VSNL1','AVIL'],
        ['ZBTB17','NEB'],
        ['ZC3H11A','REN'],
        ['ZMIZ1','MAT1A'],
        ['ZNF140','CUX2'],
        ['ZNF160','ZNF415'],
        ['ZNF195','SCUBE2'],
        ['ZNF197','CHMP2B'],
        ['ZNF564','FARSA'],
        ['ZNF564','TUT1'],
        ['ZNF787','GPR4'],
        ['ZNF804A','PHLPP1'],
        ['PTPRK','RSPO3'],
        ['PTPRK','EPB41L2'],
        ['PTPRK','BCKDHB'],
        ['NPM1','ALK'],
        ['EML4','ALK'],
        ['SLC34A2','ROS1'],
        ['CCDC6','RET'],
        ['CIC','FOXO4'],
        ['FN1','FGFR1'],
        ['CIC','DUX4'],
        ['SYT','SSX1'],
        ['SYT','SSX2'],
        ['PAX3','FOXO1'],
        ['TPM3','ALK'],
        ['TPM4','ALK'],
        ['EWS','FLI1'],
        ['LRP1','SNRNP25'],
        ['KCNMB4','CCND3'],
        ['LRP1','SNRNP25'],
        ['KCNMB4','CCND3'],
        ['MDM2','RUNX2'],
        ['TP53','CCNB1'],
        ['DPM1','CD63'],
        ['ZFC3H1','MDM2'],
        ['LRP1','SNRNP25'],
        ['TP53','AC016582.2'],
        ['DUSP14','BCAS3'],
        ['FAM120C','PAGE1'],
        ['AUTS2','GLI3'],
        ['GAPVD1','COL5A1'],
        ['KMT2C','AC006372.4'],
        ['TP53','CCNB1'],
        ['PRR5','SYT13'],
        ['HMGA2','MSRB3'],
        ['ZFC3H1','MDM2'],
        ['ERG','IFNGR2'],
        ['KCNMB4','CCND3'],
        ['MDM2','RUNX2'],
        ['IRAK3','RUNX2'],
        ['DPM1','CD63'],
        ['SHBG','CHD3'],
        ['RAD51C','ATXN7'],
        ['STRN3','JAK2'],
        ['C12ORF35','AMN1'],
        ['FAM23A','MRC1'],
        ['EBF1','PDGFRB'],
        ['SEMA6A','FEM1C'],
        ['DOCK8','CBWD2'],
        ['PAX5','ZCCHC7'],
        ['ZCCHC7','PAX5'],
        ['NUP214','ABL1'],
        ['SEMA6A','FEM1C'],
        ['TSHZ2','SLC35A1'],
        ['TPM4','KLF2'],
        ['IGH@','EPOR'],
        ['BCR','JAK2'],
        ['IGH@','CRLF2'],
        ['OAZ1','KLF2'],
        ['TPM4','KLF2'],
        ['SEMA6A','FEM1C'],
        ['SLC2A5','BTBD7'],
        ['IGH@','CRLF2'],
        ['BTBD7','SLC2A5'],
        ['IGH@','CRLF2'],
        ['ZNF292','SLC2A5'],
        ['PAX5','JAK2'],
        ['ETV6','ABL1'],
        ['RCSD1','ABL1'],
        ['ABL1','RCSD1'],
        ['NUP214','ABL1'],
        ['RANBP2','ABL1'],
        ['ZNF296','GEMIN7'],
        ['TMEM65','RP11-383J24.2'],
        ['IRF2BP2','AL672183.2'],
        ['CIITA','DEXI'],
#        ['ZNF445','RP11-101C21.1'],
        ['SPG21','ANKDD1A'],
        ['TRMT2B','ARL13A'],
        ['RABGGTA','DHRS1'],
        ['C2ORF56','PRKD3'],
        ['CD68','MPDU1'],
        ['RXFP2','ZNF828'],
        ['PDE8B','WDR41'],
        ['NSFL1C','SIRPB2'],
        ['CLN5','FBXL3'],
        ['DAZAP2','LOC57228'],
        ['OGFOD1','BBS2'],
        ['SMG5','PAQR6'],
        ['ANKRD23','CNNM3'],
        ['RUNDC2A','SNX29'],
        ['TPPP3','ZDHHC1'],
        ['PPCS','LOC728621'],
        ['RRN3P3','CDR2'],
        ['CLIP4','SAP130'],
        ['HERC3','FAM13AOS'],
        ['HNRNPU','NCRNA00201'],
        ['NDEL1','MYH10'],
        ['PLD4','AHNAK2'],
        ['CSF2RA','IL9R'],
        ['IL2RG','CXORF25'],
        ['KIAA1147','AGK'],
        ['ZNRF2','DKFZP586I1420'],
        ['ZNF319','C16ORF57'],
        ['MED12L','IGSF10'],
        ['RBED1','CAPG'],
        ['ZNF394','ZNF789'],
        ['DEGS2','IGHV@'],
        ['ATG4A','PSMD10'],
        ['DHX8','ETV4'],
        ['ATP5I','MFSD7'],
        ['NFATC3','PLA2G15'],
        ['TAF6L','TMEM179B'],
        ['EIF4E3','CICP6'],
        ['HTR1F','CICP6'],
        ['ADAP2','RNF135'],
        ['KCNK6','CATSPERG'],
        ['LST1','LTB'],
        ['MBD1','CCDC11'],
        ['MICAL2','MICALCL'],
        ['PARL','MAP6D1'],
        ['STAT5B','STAT5A'],
        ['TGFB1','HNRNPUL1'],
        ['TPM4','KLF2'],
        ['ADRB2','AC138031.1'],
        ['C14ORF49','IGHV@'],
        ['CD55','AL672183.2'],
        ['B3GNTL1','METRNL'],
        ['C17ORF85','ITGAE'],
        ['CD302','MARCH7'],
        ['PRSSL1','PALM'],
        ['SEMA6A','COMMD10'],
        ['NPM1','TYK2'],
        ['EWSR1','NFATC2'],
        ['ETV6','RUNX1'],
        ['RUNX1','ETV6'],
        ['RIC3','TRBC2'],
        ['PAX5','ELN'],
        ['TMEM38B','TRBC2'],
        ['DA750114','TRBC2'],
        ['RAD51C','ATXN7']
]



    data = fusions.get(options.organism.lower(),[])
    if data:

        #file_symbols = os.path.join(options.output_directory,'genes_symbols.txt')
        file_symbols = os.path.join(options.output_directory,'synonyms.txt')
        loci = symbols.generate_loci(file_symbols)

        genes = symbols.read_genes_symbols(file_symbols)

        d = []
        for (g1,g2) in data:
            if g1.upper() != g2.upper():
                ens1 = symbols.ensembl(g1.upper(),genes,loci)
                ens2 = symbols.ensembl(g2.upper(),genes,loci)
                if ens1 and ens2:
                    for e1 in ens1:
                        for e2 in ens2:
                            if e1 != e2:
                                d.append([e1,e2])

        data = ['\t'.join(sorted(line)) + '\n' for line in d]
        data = sorted(set(data))

        print "%d known fusion genes found in manually currated database" % (len(data),)

        if not options.skip_filter_overlap:
            ens2hugo = dict([tuple(line.rstrip('\r\n').split('\t')) for line in file(os.path.join(options.output_directory,'genes_symbols.txt'),'r').readlines() if line.rstrip('\r\n')])

            d1 = []
            overlappings = ['ensembl_fully_overlapping_genes.txt',
                            'ensembl_same_strand_overlapping_genes.txt',
                            'refseq_fully_overlapping_genes.txt',
                            'refseq_same_strand_overlapping_genes.txt',
                            "ucsc_fully_overlapping_genes.txt",
                            "ucsc_same_strand_overlapping_genes.txt",
                            'pairs_pseudogenes.txt',
                            'banned.txt',
                            'paralogs.txt']
            ensembls = set(['ensembl_fully_overlapping_genes.txt',
                            'ensembl_same_strand_overlapping_genes.txt'])
            ens = []
            for ov in overlappings:
                p = os.path.join(options.output_directory,ov)
                print "Parsing file:",p
                d2 = []
                if os.path.isfile(p):
                    d2 = sorted(set([tuple(sorted(line.rstrip('\r\n').split('\t'))) for line in file(p,'r').readlines() if line.rstrip('\r\n')]))
                    d3 = set(['\t'.join(line)+'\n' for line in d2])
                    d4 = sorted([line for line in data if line in d3])
                    d4 = [line.rstrip('\r\n').split('\t') for line in d4]
                    d4 = [line+[ens2hugo.get(line[0],'')]+[ens2hugo.get(line[1],'')] for line in d4]
                    d4 = ['\t'.join(line)+'\n' for line in d4]
                    file(os.path.join(options.output_directory,"known___%s"%(ov,)),'w').writelines(d4)
                if ov in ensembls:
                    ens.extend(d2)
                d1.extend(d2)
            d = set()
            for line in d1:
                (a,b) = (line[0],line[1])
                if a > b:
                    (a,b) = (b,a)
                d.add("%s\t%s\n" % (a,b))
            ens = set(['\t'.join(line)+'\n' for line in ens])
            ensembl = [line for line in data if line in ens]
            file(os.path.join(options.output_directory,'known___ensembl.txt'),'w').writelines(sorted(ensembl))
            skipped = [line for line in data if line in d]
            data = [line for line in data if line not in d]
            file(os.path.join(options.output_directory,'known___all.txt'),'w').writelines(sorted(skipped))

            print "%d known fusion genes left after removing the overlappings" % (len(data),)

    file(os.path.join(options.output_directory,'known.txt'),'w').writelines(sorted(data))
    #
